St. Louis Cardinals @ Philadelphia Phillies Player Props, Picks and Predictions - 5/12/2025 6:45 PM EDT

We have your St. Louis Cardinals @ Philadelphia Phillies prop betting and game preview needs covered as the Philadelphia Phillies hit the road to face the St. Louis Cardinals.

St. Louis Cardinals @ Philadelphia Phillies Pick

Best Moneyline Odds: Phillies -185 | Cardinals +155
Best Spread Odds: Phillies -1.5 (+115) | Cardinals +1.5 (-137)
Best Total Odds: Over 8 (-115) | Under 8 (-105)

Game Info

Date: May 12, 2025
Time: 6:45 PM EDT
Location: Busch Stadium, St. Louis, MO
TV: -

St. Louis Cardinals @ Philadelphia Phillies Preview

The Philadelphia Phillies come into this matchup as slight favorites, boasting a 20-12 record as moneyline favorites this season. They are fresh off a 3-0 victory over the Cleveland Guardians, showcasing their pitching depth and offensive consistency. The St. Louis Cardinals, on the other hand, are riding high after a 6-1 win against the Washington Nationals, with their offense firing on all cylinders. This game could be pivotal for both teams as they look to solidify their standings in the National League.

Historic Head-to-Head Stats and Analysis

In their last 10 meetings, the Phillies have had the upper hand, winning 6 of those matchups. The Cardinals, however, have been competitive at home, splitting their last 4 games against the Phillies at Busch Stadium. Historically, these games have been tightly contested, with an average total of 7.8 runs per game, slightly below the set total for this matchup.

Pick: Phillies Moneyline (-185)

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The Phillies have been dominant as favorites this season, winning 62.5% of such games. Their recent form, combined with a strong pitching rotation, gives them the edge in this matchup. While the Cardinals have shown flashes of brilliance, the Phillies' consistency and ability to perform under pressure make them the safer pick for this game.

Top Player Prop Picks

1. Bryce Harper Over 1.5 Total Bases (+120)

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Harper has been in excellent form, consistently delivering at the plate. With his ability to hit for power and find gaps, he is a strong candidate to exceed this line, especially against a Cardinals pitching staff that has struggled against left-handed hitters.

2. Nolan Arenado Over 0.5 RBIs (+110)

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Arenado has been a key contributor for the Cardinals, particularly in clutch situations. With runners likely to be on base, Arenado's ability to drive in runs makes this a solid prop bet.

3. Zack Wheeler Over 6.5 Strikeouts (-105)

Wheeler has been a strikeout machine this season, averaging over 7 strikeouts per game. Facing a Cardinals lineup that has been prone to strikeouts, Wheeler is well-positioned to hit this mark.

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