St. Louis Cardinals @ Los Angeles Dodgers Player Props, Picks and Predictions - 8/6/2025 4:10 PM EDT

We have your St. Louis Cardinals @ Los Angeles Dodgers prop betting and game preview needs covered as the St. Louis Cardinals hit the road to face the Los Angeles Dodgers.

St. Louis Cardinals @ Los Angeles Dodgers Pick

Best Moneyline Odds: Los Angeles Dodgers -205 (ESPN BET)
Best Spread Odds: Los Angeles Dodgers -1.5 (+100 BetMGM)
Best Total Odds: Over 9.0 (-124 BetRivers)

Game Info

Date: 2025-08-06
Time: 4:10 PM EDT
Location: Dodger Stadium, Los Angeles, CA
TV: FDSMW

St. Louis Cardinals @ Los Angeles Dodgers Preview

The Los Angeles Dodgers (66-48) are set to host the St. Louis Cardinals (57-58) in a rubber match at Dodger Stadium. The Dodgers lead the NL West, while the Cardinals are fourth in the NL Central. Los Angeles is coming off a dominant 12-6 victory over the Cardinals, showcasing an explosive offensive awakening with 17 hits. This comes after a period of inconsistency, highlighted by Max Muncy's two home runs and Mookie Betts breaking out of a slump with three hits. The Dodgers boast a strong hitting lineup, ranking 3rd in on-base percentage and slugging percentage, and 2nd in the league with 165 home runs.

On the mound for the Dodgers will be two-way superstar Shohei Ohtani, making his seventh start of the season. Ohtani (0-0, 2.40 ERA) is expected to be limited to around four innings as he continues to build arm strength following his Tommy John revision surgery. His last outing was a bit shaky, but his overall effectiveness as a pitcher is evident in his low ERA. At the plate, Ohtani enters the game on a five-game hitting streak, indicating he's finding his rhythm.

The St. Louis Cardinals will counter with left-hander Matthew Liberatore (6-9, 3.96 ERA). Liberatore has been a steady presence in the Cardinals' rotation, allowing two or fewer earned runs in six of his last seven starts. His ability to limit walks (1.27 WHIP) is a key asset. However, this will be Liberatore's first career start against the Dodgers, and he has a 7.27 ERA in six previous relief appearances against them, suggesting a challenging matchup against Los Angeles' powerful offense.

Historic Head-to-Head Stats and Analysis

The recent history between these two clubs has been competitive. The St. Louis Cardinals won the June series against the Dodgers in St. Louis. More recently, the Cardinals secured a thrilling 3-2 victory in Game 1 of this current series in Los Angeles, winning as underdogs. However, the Dodgers responded emphatically with a 12-6 win in the most recent game on August 5th.

Looking at past matchups, two out of their previous four meetings finished with under five total runs combined, indicating that these teams can engage in low-scoring pitching duels. In his only career start against the Cardinals, Shohei Ohtani was electric, striking out 13 batters, though he did give up four runs. For Matthew Liberatore, while this is his first career start against the Dodgers, his previous six relief appearances against them saw him post a high 7.27 ERA.

Pick: Los Angeles Dodgers Moneyline

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The Los Angeles Dodgers are the clear favorites in this matchup, and for good reason. Our model projects the Dodgers to win with a score of 6-4, and sharp betting insights show a 65.28% win probability for the Dodgers on the moneyline. While Shohei Ohtani is still being ramped up on the mound, his 2.40 ERA demonstrates his effectiveness, and the Dodgers' offense has shown signs of breaking out of its slump, as evidenced by their 12-6 victory in the previous game. The Cardinals' starter, Matthew Liberatore, has struggled against the Dodgers in relief appearances, and facing their potent lineup in his first career start against them could prove challenging. Given the Dodgers' offensive firepower, Ohtani's presence, and the home-field advantage, backing the Los Angeles Dodgers to win straight up at -205 odds on ESPN BET is the recommended pick.

Top Player Prop Picks

Freddie Freeman - Over 1.5 Hits + Runs + RBIs

Freddie Freeman has been a consistent offensive force for the Dodgers, especially at home. He has hit the over on this line in 100% of his last 5 games and 80% of his last 10 games, with a mean of 3.6 and 3.1 respectively. For the season, his average is 2.32 Hits + Runs + RBIs, well above the 1.5 line. When playing at Dodger Stadium this season, he has hit the over 51.85% of the time. Given his recent hot streak and strong home performance, taking the over on Freddie Freeman's Hits + Runs + RBIs at 1.5 with -160 odds on DraftKings is a strong play.

Nolan Gorman - Over 0.5 Hits + Runs + RBIs

Nolan Gorman has been performing exceptionally well recently, hitting the over on this prop in 100% of his last 5 games and 80% of his last 10 games. His season mean for Hits + Runs + RBIs is 1.64, significantly higher than the 0.5 line. More impressively, against the Los Angeles Dodgers in 2025, he has hit the over in 100% of his 2 appearances, with a mean of 4.0. In 2024, he hit the over in 80% of his 5 games against them. This consistent performance against the Dodgers makes the over on Nolan Gorman's Hits + Runs + RBIs at 0.5 with -135 odds on BetMGM a compelling pick.

Masyn Winn - Over 0.5 Hits

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Masyn Winn has demonstrated a strong ability to get on base, hitting the over on 0.5 hits in 60% of his last 5 games and 70% of his last 10 games. His season average for hits is 1.03, comfortably above the 0.5 line. Against the Los Angeles Dodgers, Winn has a particularly strong record, hitting the over in 80% of his 5 appearances in 2025 and 66.67% of his 6 appearances in 2024. His consistent hitting, especially against this opponent, makes the over on Masyn Winn's Hits at 0.5 with -160 odds on BetMGM a favorable bet.