If you love epic comebacks, Week 5 in the NFL was for you.

The Broncos pulled off one of the biggest upsets of the day by scoring 11 unanswered points in the 4th Quarter, giving the Eagles their first loss since December 2024. The Titans picked up their first win of the season, coming back from a 21-3 deficit against the Cardinals, which was aided by Cardinals running back Emari Demercado letting go of the ball just before the goal line.

Many of these unexpected results meant a bad day for Favorites, as they not only went 5-9 Against the Spread, but also 5-9 Straight Up. It was even worse for the Home Teams, which went 4-10 ATS and SU. As for Totals, it was all about scoring in Week 5, as the Overs went 9-5.

Pickwatch Experts

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To get all of our Expert Picks, you must have a Pickwatch Pro subscription. To see the team-by-team expert rankings and additional data, you’re required to have a Pickwatch Expert subscription. Lastly, if you want access to valuable sports betting tools, in addition to Expert Picks data, try the Pickwatch BetSmart subscription FREE for 14 days.

Expert of the Week: Ryan Wilson

Our Expert of the Week is Ryan Wilson of CBS Sports. Pickwatch has been tracking Wilson since 2014, and he’s definitely someone you should be following this season.

Wilson has a notable history of success, finishing in the Top 50 of NFL ATS experts in both 2016 and 2017. He has a winning rate of 60% or higher in eight different weeks when choosing NFL ATS. Although his focus is solely on ATS, he has secured over a 50% win rate across more than 2,500 picks in his career.

For the 2025 NFL season, Wilson remains someone to watch. He’s been successful, with 57.7% ATS, and ranks seventh among all NFL ATS experts; his 45 correct picks are the 3rd most.

Ryan Wilson NFL Picks Breakdown

Week 5 Record (ATS): 9-5 (20th)
Overall Record (ATS): 45-33 (7th)
Ryan Wilson Pickwatch Expert Page

Week 5 Overview

In Week 5 of the NFL, it was another winning week for Wilson at 9-5, which was good enough for the 7th-best record. These were highlighted by a couple of great predictions.

He nailed a couple of big spreads, including Lions -10.5 and Colts -6.5. One of the more notable picks Wilson had was the Broncos +3.5, which went into Philly and completed the upset.

Additional Sports & Leagues

While Wilson only has NFL picks tracked by Pickwatch, many other experts cover a wide variety of sports. Whether you want MLB picks for the playoffs or are looking forward to the start of the NBA season, keep in mind Pickwatch tracks the top experts in those sports and many more.

Unlock Expert Picks and More Today

If you want Expert Picks from Wilson and hundreds of others for all the major sports and leagues around the world, sign up for a subscription today. With a Pickwatch Pro subscription, you gain access to all the picks from the top experts, whereas with a Pickwatch Expert subscription, you also get team-by-team rankings and additional expert data.

If you want to take things to the next level as a profitable sports bettor, you should consider a BetSmart subscription, where you will also get access to several sports betting tools, such as:

The best part is that it comes with a FREE 14-day trial. So sign up today and take advantage of this limited-time offer.