Here is the Pickwatch BetSmart Preview for the Philadelphia Eagles vs. Los Angeles Chargers game in Week 14 of the 2025 NFL Season.

Philadelphia Eagles vs. Los Angeles Chargers Game Info

Date: Monday, December 8, 2025
Time: 8:15 PM ET
Location: SoFi Stadium — Inglewood (Los Angeles), California
TV: ESPN/ABC

Eagles vs. Chargers Betting Odds

Point Spread
- Eagles -2.5
- Chargers +2.5
Moneyline
- Eagles -140
- Chargers +120
Total
- Over/Under 41.5

Season Betting Records

Moneyline
- Eagles: 8-4
- Chargers: 8-4
Against the Spread
- Eagles: 7-5
- Chargers: 5-6-1
Totals (Over-Under)
- Eagles: 5-7
- Chargers: 6-6

Philadelphia Eagles (8-4) @ Los Angeles Chargers (8-4) Preview

The Eagles head west for a difficult primetime matchup in Los Angeles, bringing with them an offense that has looked sharper in recent weeks. Jalen Hurts is moving better, the RPO game has returned to form, and the offensive line—despite missing starters—has played more cohesively. Indoors at SoFi, the Eagles’ scheme tends to operate at full speed, allowing for more vertical concepts and deeper intermediate shots to A.J. Brown and DeVonta Smith.

The Chargers counter with an offense built on spacing, tempo, and explosive passing windows. Their success tonight will hinge heavily on pass protection; when the Chargers’ line holds, their quarterback can attack Philadelphia’s banged-up secondary with layered route concepts. Defensively, Los Angeles will mix coverages to slow Brown while sending pressure selectively, trying to force Hurts into hurried throws and prevent extended scramble plays.

Injury-wise, both teams are dealing with notable absences. The Eagles are without Lane Johnson, Andrew Mukuba, Myles Hinton, and special-teams weapon Xavier Gipson, thinning both trenches and their defensive backfield. The Chargers enter with injuries across their offensive line, at wide receiver, and in the secondary—forcing them to rely on depth players in high-leverage moments. Indoors, weather is irrelevant, but injuries will have a major influence on the matchups and expected scoring.

From a betting standpoint, the Eagles come in as deserved favorites based on form and consistency, but the Chargers at home—under the dome at SoFi—have the offensive upside to turn this into a shootout if they protect the quarterback. Expect a game defined by explosive plays, red-zone execution, and which defense can create one or two timely stops.

Eagles/Chargers Head-to-Head (H2H) Stats and Analysis

The Los Angeles Chargers lead the all-time series 8–5 vs. the Philadelphia Eagles. Here are the last 5 meetings:

Los Angeles Chargers 27, Philadelphia Eagles 24 — November 7, 2021
Philadelphia Eagles 26, Los Angeles Chargers 24 — October 1, 2017
San Diego Chargers 33, Philadelphia Eagles 30 — September 15, 2013
San Diego Chargers 31, Philadelphia Eagles 23 — November 15, 2009
Philadelphia Eagles 20, San Diego Chargers 17 — October 23, 2005

BetSmart Betting Rundown

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NOTE: All available bets are as of time of publication. Odds and lines change often, so be sure to check each subsequent Pickwatch betting tool for the latest numbers.

Arbitrage

Our Arbitrage Betting Tool is currently identifying 2 arbitrage betting opportunities for guaranteed profit.

Middles

Our Middle Betting Tool is currently identifying 49 middle betting opportunities.

Positive EV

Our Positive EV Betting Tool is currently identifying 11 different positive expected value wagers, and provided data on the expected value percentrage, and how often the bet has hit in the last 5, 10 and 15 games.

Player Props

Our Prop Finder Tool is currently identifying 260 different player prop bets, and provided data on how often each player has hit the specific prop in the last 5, 10 and 15 games.

Eagles vs. Chargers: Expert Picks

Visit our Expert Picks page to view picks and data from over 200 experts to see where the consensus is on the Eagles vs. Chargers moneyline, point spread and total points.