Minnesota Twins @ Cleveland Guardians Player Props, Picks and Predictions - 4/30/2025 6:10 PM EDT

We have your Minnesota Twins @ Cleveland Guardians prop betting and game preview needs covered as the Cleveland Guardians hit the road to face the Minnesota Twins.

Minnesota Twins @ Cleveland Guardians Pick

Best Moneyline Odds: Minnesota Twins -130, Cleveland Guardians +110.
Best Total Odds: Over/Under 7 runs (-120 for Over, +100 for Under).

Game Info

Date: April 30, 2025
Time: 6:10 PM EDT
Location: Target Field, Minneapolis, MN
TV: -

Minnesota Twins @ Cleveland Guardians Preview

The Minnesota Twins and Cleveland Guardians face off in a pivotal AL Central matchup. The Twins come into this game as slight favorites, having won six of their last seven games. Meanwhile, the Guardians have struggled recently, going 1-4 in their last five games. Both teams are looking to gain ground in the division standings, making this a critical game for both sides.

Historic Head-to-Head Stats and Analysis

In their last 16 meetings, the Under has hit 10 times, with 4 Overs and 2 pushes. The Twins have been dominant in recent matchups, winning 6 of their last 7 games against the Guardians. Cleveland, however, managed to edge out a 2-1 victory in their most recent game on April 29, 2025.

Pick: Minnesota Twins Moneyline (-130)

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The Twins have been in excellent form, winning 6 of their last 7 games. Their recent dominance over the Guardians, combined with Cleveland's struggles (1-4 in their last 5 games), makes the Twins a strong pick to win this matchup. Additionally, Minnesota's ability to perform under pressure in close games gives them the edge in this contest.

Top Player Prop Picks

1. Over 1.5 Total Bases for Byron Buxton (+120)

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Byron Buxton has been a key offensive contributor for the Twins, and his ability to hit for extra bases makes this prop appealing. With Cleveland's pitching staff struggling recently, Buxton is well-positioned to capitalize and exceed this line.

2. Over 5.5 Strikeouts for Pablo López (-110)

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Pablo López has been a strikeout machine this season, consistently racking up Ks against opposing lineups. Facing a Cleveland team that has struggled offensively, López should have ample opportunities to hit this mark.

3. Under 0.5 Hits for José Ramírez (+150)

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José Ramírez is one of Cleveland's most dangerous hitters, but he faces a tough matchup against Pablo López, who has been dominant against right-handed batters. This high-value prop is worth considering given the pitching matchup.

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