Milwaukee Brewers @ Chicago Cubs Player Props, Picks and Predictions - 8/19/2025 2:20 PM EDT

We have your Milwaukee Brewers @ Chicago Cubs prop betting and game preview needs covered as the Milwaukee Brewers hit the road to face the Chicago Cubs.

Milwaukee Brewers @ Chicago Cubs Pick

Best Moneyline Odds: Chicago Cubs -140 (Caesars), Milwaukee Brewers +130 (ESPN BET)
Best Spread Odds: Chicago Cubs -1.0 (-103) (DraftKings), Milwaukee Brewers +1.5 (-170) (Fanduel)
Best Total Odds: Over 7.0 (-106) (Fanduel), Under 7.5 (-145) (ESPN BET)

Game Info

Date: Tuesday, August 19th 2025
Time: 2:20 PM ET
Location: Wrigley Field, Chicago, Illinois
TV: MARQ

Milwaukee Brewers @ Chicago Cubs Preview

The Milwaukee Brewers, holding a strong 79-45 record and leading the NL Central, are set to face the Chicago Cubs (70-54) in a crucial doubleheader at Wrigley Field. The Brewers enter this contest on a hot streak, having won 9 of their last 10 games, including a dominant 7-0 victory over the Cubs on Monday. This recent success highlights their momentum as they look to solidify their division lead.

For the first game of the doubleheader, the Brewers are expected to start Chad Patrick (3-7, 3.52 ERA), while the Cubs will counter with Matthew Boyd (11-6, 2.46 ERA). Boyd has historically struggled against the Brewers, holding a career ERA of 9.68 in four starts against them. This could present an opportunity for Milwaukee's offense, which ranks second in batting average (.259) and on-base percentage (.331) and is known for its strong baserunning pressure. Key offensive players for the Brewers include Christian Yelich, who leads the offense, along with Brice Turang, Sal Frelick, Andrew Vaughn, Isaac Collins, Joey Ortiz, Caleb Durbin, Blake Perkins, and William Contreras, who has been particularly impressive recently.

The Cubs, despite their respectable overall record, have shown inconsistent offensive performance lately, averaging just 2.6 runs per game over their last 10 matchups. Their lineup features powerful hitters like Seiya Suzuki, Michael Busch, and Pete Crow-Armstrong, but they have experienced stretches of big innings followed by long scoreless periods. Wrigley Field, with a park factor of 96 (2023-2025), is generally slightly pitcher-friendly, though warm and humid conditions can help the ball carry. Bullpen management will be critical for both teams in this doubleheader, with the Brewers holding an edge in recent bullpen ERA compared to the Cubs' shaky middle relief.

Historic Head-to-Head Stats and Analysis

The rivalry between the Milwaukee Brewers and Chicago Cubs has a rich history, with the Brewers currently leading the all-time series 229-223. In recent seasons, Milwaukee has had the upper hand, winning the season series against the Cubs in the last two years (8-5 last season and 7-6 the year prior). The 2025 season series between these two teams is currently tied at 4-4, indicating a closely contested matchup this year.

Historically, the Cubs have secured 71 wins against the Brewers at home, while the Brewers have claimed 81 victories on the road against the Cubs, including 41 at Wrigley Field. This suggests that Milwaukee has found success when playing away from home against Chicago. Their most recent encounter on August 18 saw the Brewers dominate with a 7-0 victory. Despite the Cubs often playing the Brewers tough, leading to frequent series splits, the Brewers have demonstrated a notable ability to win at Wrigley Field, having secured 5 wins in their last 6 games at the Cubs' home ballpark.

Pick: Under 7.0 Total Runs

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Considering the pitching matchup and recent trends, the recommendation for this game is to take the Under 7.0 total runs. While the Brewers' offense has been potent, Matthew Boyd, despite his career struggles against Milwaukee, has a strong 1.75 ERA at Wrigley Field this season. On the other side, Chad Patrick, though having a higher ERA, has shown flashes of command. The overall strong pitching from both sides, combined with the general pitcher-friendly nature of Wrigley Field (Park Factor of 96), suggests a lower-scoring affair. My model projects a total of 7 runs, aligning with the under line, making it a compelling pick given the strong pitching on display.

Top Player Prop Picks

Chad Patrick - Pitcher Strikeouts Over 4.5

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Milwaukee Brewers pitcher Chad Patrick has demonstrated a strong strikeout ability recently, hitting the over in 80% of his last 5 games (averaging 6.4 strikeouts) and 80% of his last 10 games (averaging 5.9 strikeouts). While his performance on the road this season has seen him hit the over in only 25% of his starts, his last outing against the Cubs in 2025 resulted in him hitting the over on this line. With a season average of 5.0 strikeouts, the line of 4.5 seems attainable for Patrick. You can find the best odds for this prop at -117 on Caesars.

Joey Ortiz - Hits + Runs + RBIs Over 0.5

Joey Ortiz of the Milwaukee Brewers has been a consistent contributor to his team's offense, hitting the over on his Hits + Runs + RBIs prop in 60% of his last 5 games (averaging 2.8) and an impressive 80% over his last 10 and 15 games. When playing on the road, Ortiz has hit the over in 67.8% of his games this season, averaging 2.07 Hits + Runs + RBIs. While his 2025 performance against the Cubs has seen him hit the over in 44.44% of games, his overall recent form and road performance make the over 0.5 line attractive. The best odds for this prop are -185 on BetMGM.

William Contreras - Hits Over 0.5

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William Contreras, a key offensive player for the Milwaukee Brewers, has been in excellent hitting form. He has hit the over on his Hits prop in 80% of his last 5 games (averaging 1.2 hits) and 80% of his last 10 games (averaging 1.4 hits). For the entire season, Contreras has hit the over in 63.56% of his games, with an average of 0.97 hits. Notably, against the Chicago Cubs in 2025, he has hit the over in 77.78% of his matchups, averaging 1.22 hits. His strong performance on the road this season, hitting the over in 70% of games, further supports this pick. You can find the best odds for this prop at -200 on Fanduel.

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