Here is the Pickwatch BetSmart Preview for the Los Angeles Rams vs. Seattle Seahawks game in Week 16 of the 2025 NFL Season.

Los Angeles Rams vs. Seattle Seahawks Game Info

Date: Thursday, December 18, 2025
Time: 8:15 PM ET
Location: Lumen Field — Seattle, Washington
TV: Amazon Prime Video

Falcons vs. Bucs Betting Odds

Point Spread
- Rams +1.5
- Seahawks -1.5
Moneyline
- Rams +110
- Seahawks -130
Total
- Over/Under 44.5

Season Betting Records

Moneyline
- Rams: 11-3
- Seahawks: 11-3
Against the Spread
- Rams: 10-4
- Seahawks: 10-4
Totals (Over-Under)
- Rams: 7-7
- Seahawks: 8-6

Los Angeles Rams (10-4) @ Seattle Seahawks (10-4) Preview

Seattle returns home for a critical NFC West matchup under the lights, where they’ve historically played with added defensive intensity and crowd-driven momentum. The Seahawks’ offense has leaned on balance this season, but consistency—especially in the red zone—has been the swing factor in recent weeks. At home on a short week, expect Seattle to emphasize early tempo and physicality to seize control.

The Rams arrive in Seattle accustomed to close games against this opponent, relying on efficiency, play-action, and situational execution rather than raw explosiveness. Their offense has been at its best when staying ahead of the chains, using motion and quick reads to neutralize pressure. Against Seattle’s aggressive front, protection and third-down conversion will dictate whether Los Angeles can sustain drives.

Weather could be a factor at Lumen Field, with cool temperatures and potential rain and wind affecting the passing game. From a betting perspective, Seattle’s home-field edge and defensive pressure make them a popular side, but the Rams’ ability to keep games close keeps the spread tight. Expect another physical, one-score NFC West battle that likely comes down to late-game execution and turnover margin.

Rams/Seahawks Head-to-Head (H2H) Stats and Analysis

The Los Angeles Rams are tied with Seattle Seahawks in the all-time series 28-28. Here's their last 5 games:

Los Angeles Rams 21, Seattle Seahawks 19 — November 16, 2025
Seattle Seahawks 30, Los Angeles Rams 25 — January 5, 2025
Los Angeles Rams 26, Seattle Seahawks 20 — November 3, 2024
Los Angeles Rams 17, Seattle Seahawks 16 — November 19, 2023
Los Angeles Rams 30, Seattle Seahawks 13 — September 10, 2023

BetSmart Betting Rundown

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NOTE: All available bets are as of time of publication. Odds and lines change often, so be sure to check each subsequent Pickwatch betting tool for the latest numbers.

Arbitrage

Our Arbitrage Betting Tool is currently identifying 2 arbitrage betting opportunities for guaranteed profit.

Middles

Our Middle Betting Tool is currently identifying 23 middle betting opportunities.

Positive EV

Our Positive EV Betting Tool is currently identifying 13 different positive expected value wagers, and provided data on the expected value percentrage, and how often the bet has hit in the last 5, 10 and 15 games.

Player Props

Our Prop Finder Tool is currently providing data for 282 different player prop bets, showing subscribers how often each player has hit the specific prop in the last 5, 10 and 15 games.

Rams vs. Seahawks: Expert Picks

Visit our Expert Picks page to view picks and data from over 200 experts to see where the consensus is on the Rams vs. Seahawks moneyline, point spread and total points.