Houston Astros @ Pittsburgh Pirates Player Props, Picks and Predictions - 6/5/2025 6:40 PM EDT

We have your Houston Astros @ Pittsburgh Pirates prop betting and game preview needs covered as the Pittsburgh Pirates host the Houston Astros in what promises to be an exciting matchup.

Houston Astros @ Pittsburgh Pirates Pick

Best Moneyline Odds: Houston Astros -155, Pittsburgh Pirates +140
Best Total Odds: Over/Under 7.5 (-111 for both over and under)

Game Info

Date: June 5, 2025
Time: 6:40 PM EDT
Location: PNC Park, Pittsburgh, PA
TV: -

Houston Astros @ Pittsburgh Pirates Preview

The Houston Astros and Pittsburgh Pirates face off in the second game of their series at PNC Park. The Pirates took the first game with a 3-0 shutout, showcasing their pitching strength and defensive prowess. The Astros, however, remain a formidable team with a strong lineup and will look to bounce back in this matchup. Both teams are vying for momentum as the season progresses, making this game critical for their standings.

Historic Head-to-Head Stats and Analysis

In their recent head-to-head matchups, the Astros have generally had the upper hand, winning six of their last eight meetings against the Pirates. However, the Pirates' victory in the previous game demonstrates their ability to compete against Houston, especially at home. The total has gone under in 16 of the last 24 games between these two teams, indicating a trend toward lower-scoring contests.

Pick: Houston Astros Moneyline (-155)

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The Astros are the favorites in this matchup, and for good reason. Despite their loss in the previous game, Houston's lineup is packed with offensive firepower, and they have a strong track record against the Pirates. The Pirates' pitching staff will need to replicate their stellar performance from the last game to keep Houston at bay, but the Astros' ability to adjust and capitalize on opportunities makes them the safer pick for this game.

Top Player Prop Picks

1. Framber Valdez Over 6.5 Strikeouts (-110)

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Valdez is a strikeout machine and has consistently hit this mark in recent outings. Against a Pirates lineup that can struggle with strikeouts, this prop offers solid value.

2. Bryan Reynolds Over 1.5 Total Bases (+120)

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Reynolds has been a key offensive contributor for the Pirates and is coming off a strong performance in the previous game. Look for him to continue his hot streak at the plate.

3. Kyle Tucker Over 0.5 Home Runs (+400)

Tucker has the power to change the game with one swing, and PNC Park's dimensions could work in his favor. At these odds, this is a high-upside play worth considering.

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