Florida International Panthers @ Penn State Nittany Lions Player Props, Picks and Predictions - 9/6/2025 12:00 PM EDT

We have your Florida International Panthers @ Penn State Nittany Lions prop betting and game preview needs covered as the Florida International Panthers hit the road to face the Penn State Nittany Lions.

Florida International Panthers @ Penn State Nittany Lions Pick

Best Moneyline Odds: Penn State -100000 at Fanduel | Florida International +8000 at Fanduel
Best Spread Odds: Penn State -42.5 (-110) at BetRivers
Best Total Odds: Over 56.0 (-114) at BetRivers | Under 56.5 (-105) at Fanduel

Game Info

Date: 2025-09-06
Time: 12:00 PM EDT
Location: Beaver Stadium, State College, PA
TV: -

Florida International Panthers @ Penn State Nittany Lions Preview

The Penn State Nittany Lions enter this matchup with sky-high expectations for the 2025 season, following a dominant 46-11 victory over Nevada in their opener. Quarterback Drew Allar had a sterling debut, completing 22 of 26 passes for 217 yards and a touchdown, quickly establishing a connection with transfer wide receiver Kyron Hudson. However, the true standout was Penn State's defense, which stifled Nevada's offense, holding them to just 78 rushing yards and generating three sacks and nine tackles for loss. Dani Dennis-Sutton was particularly disruptive, recording a sack, 2.5 tackles for loss, and two forced fumbles. The Nittany Lions are expected to be favored in 11 of their 12 games this season and hold the best odds (+420) to finish undefeated, according to FanDuel Sportsbook. Their strong performance against Nevada, where they covered a -44.5 point spread, underscores their potential.

The Florida International Panthers also started their season with a win, defeating Bethune-Cookman 42-9. FIU's offense showed promise, accumulating 223 rushing yards and 233 passing yards for a total of 456 yards. Their defense allowed only 9 points and 346 total yards. While these statistics are encouraging, they came against a significantly less challenging opponent. FIU will face a massive step up in competition against a Penn State team that appears to be one of the nation's elite.

Historic Head-to-Head Stats and Analysis

The Florida International Panthers and Penn State Nittany Lions have met only once before. In that previous encounter, the Nittany Lions defeated the Panthers with a decisive 59-0 victory.

Pick: Penn State -42.5

Penn State's Week 1 performance against Nevada was a clear statement of their intentions for the season. They not only secured a comfortable 46-11 win but also covered a substantial -44.5 point spread, demonstrating their ability to dominate weaker opponents. Quarterback Drew Allar looked sharp, and the Nittany Lions' defense was stifling, controlling the line of scrimmage and limiting Nevada's offensive production. This defensive prowess, combined with an efficient offense, makes them a formidable force.

Historically, Penn State has been a reliable bet when favored, boasting a 69.7% ATS (Against The Spread) cover rate over the last four seasons in such situations. Their overall ATS record stands at 64-43 (59.8%). While Florida International secured a win in their opener, their statistics were against a much lower-tier opponent. The talent gap between these two programs is significant, and Penn State's home-field advantage will only amplify this disparity. Expect the Nittany Lions to maintain their aggressive play and comfortably cover the large spread against the Panthers.