Athletics @ Chicago White Sox Player Props, Picks and Predictions - 4/16/2025 7:40 PM EDT

We have your Athletics @ Chicago White Sox prop betting and game preview needs covered as the Chicago White Sox hit the road to face the Athletics.

Athletics @ Chicago White Sox Pick

Best Moneyline Odds: Athletics -162, White Sox +140
Best Spread Odds: Athletics -1.5 (+100), White Sox +1.5 (-120)
Best Total Odds: Over 8 (-110), Under 8 (-110)

Game Info

Date: April 16, 2025
Time: 7:40 PM EDT
Location: Oakland Coliseum, Oakland, CA
TV: -

Athletics @ Chicago White Sox Preview

The Athletics and White Sox face off in the second game of their series after the Athletics dominated the first game with a 12-3 victory. The Athletics' offense exploded, showcasing their ability to capitalize on opportunities, while the White Sox struggled to keep up. Both teams will look to make adjustments as they head into this matchup. The Athletics are slight favorites, and their recent performance suggests they have the momentum heading into this game.

Historic Head-to-Head Stats and Analysis

In their most recent matchup on April 15, 2025, the Athletics defeated the White Sox 12-3 in a commanding performance. Historically, the Athletics have had the upper hand in this series, winning the majority of their recent encounters. The White Sox will need to improve their pitching and defense to turn the tide in this matchup.

Pick: Athletics Moneyline (-162)

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The Athletics are coming off a dominant win and have shown consistency in their recent performances. Their offense is clicking, and they have the edge in this matchup. While the White Sox will look to bounce back, the Athletics' momentum and home-field advantage make them the safer pick on the moneyline.

Top Player Prop Picks

1. Athletics' Starting Pitcher Over 6.5 Strikeouts (-110)

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The Athletics' starting pitcher has been in excellent form, consistently racking up strikeouts. With the White Sox struggling offensively in the previous game, this line is achievable.

2. Athletics' Lead-Off Hitter Over 1.5 Total Bases (+120)

The Athletics' lead-off hitter has been a key contributor, with multiple hits in recent games. Facing a White Sox pitching staff that struggled in the last game, this prop offers value.

3. White Sox Total Runs Under 3.5 (-115)

Given the White Sox's offensive struggles in the previous game and the Athletics' strong pitching, this under bet is a solid option.

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