St. Louis Cardinals @ Pittsburgh Pirates Player Props, Picks and Predictions - 7/1/2025 6:40 PM EDT

We have your St. Louis Cardinals @ Pittsburgh Pirates prop betting and game preview needs covered as the St. Louis Cardinals hit the road to face the Pittsburgh Pirates.

St. Louis Cardinals @ Pittsburgh Pirates Pick

Best Moneyline Odds: Pittsburgh Pirates -170, St. Louis Cardinals +140
Best Spread Odds: Pittsburgh Pirates -1.5 (+130), St. Louis Cardinals +1.5 (-146)
Best Total Odds: Over/Under 8.5 (-110)

Game Info

Date: July 1, 2025
Time: 6:40 PM EDT
Location: PNC Park, Pittsburgh, PA
TV: -

St. Louis Cardinals @ Pittsburgh Pirates Preview

The Pittsburgh Pirates are coming off a dominant 7-0 victory over the St. Louis Cardinals in the series opener. The Pirates showcased their offensive firepower and pitching depth, while the Cardinals struggled to find any rhythm at the plate. With the Pirates looking to build on their momentum and the Cardinals aiming to bounce back, this matchup promises to be an intriguing battle. The Pirates have been solid at home, and their recent form gives them an edge heading into this game.

Historic Head-to-Head Stats and Analysis

In their last 10 meetings, the Pittsburgh Pirates have won 6 games, while the St. Louis Cardinals have taken 4. The Pirates have been particularly strong at home, winning 4 of their last 5 games against the Cardinals at PNC Park. The Cardinals, however, have historically been a tough opponent, boasting a 10-3 record in their last 13 games prior to this series. This head-to-head history suggests a competitive matchup, but the Pirates' recent form and home-field advantage could play a significant role.

Pick: Pittsburgh Pirates Moneyline (-170)

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The Pirates are riding high after their convincing win in the series opener and have the advantage of playing at home. Their pitching staff has been effective, and their offense has been consistent. The Cardinals, on the other hand, have struggled to generate runs, as evidenced by their shutout loss in the previous game. Backing the Pirates on the moneyline is a solid choice given their current momentum and home-field edge.

Top Player Prop Picks

1. Paul Skenes Over 7.5 Strikeouts (+110)

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Paul Skenes has been a strikeout machine, and with the Cardinals' offense struggling, he is well-positioned to rack up strikeouts. His ability to dominate opposing lineups makes this a strong value play.

2. Bryan Reynolds Over 1.5 Total Bases (+120)

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Bryan Reynolds has been a key contributor for the Pirates, and his ability to hit for extra bases makes this prop appealing. With the Cardinals' pitching staff under pressure, Reynolds could capitalize on scoring opportunities.

3. Jack Suwinski to Hit a Home Run (+400)

Jack Suwinski has shown power at the plate, and with the Cardinals' pitching staff vulnerable, he has a good chance to go deep in this game. This high-value prop is worth considering for those looking for a big payout.

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