St. Louis Cardinals @ Pittsburgh Pirates Player Props, Picks and Predictions - 6/30/2025 6:40 PM EDT

We have your St. Louis Cardinals @ Pittsburgh Pirates prop betting and game preview needs covered as the St. Louis Cardinals hit the road to face the Pittsburgh Pirates.

St. Louis Cardinals @ Pittsburgh Pirates Pick

Best Moneyline Odds: St. Louis Cardinals -125, Pittsburgh Pirates +105
Best Spread Odds: Cardinals -1.5 (+140), Pirates +1.5 (-160)
Best Total Odds: Over 8.5 (-110), Under 8.5 (-110)

Game Info

Date: June 30, 2025
Time: 6:40 PM EDT
Location: PNC Park, Pittsburgh, PA
TV: -

St. Louis Cardinals @ Pittsburgh Pirates Preview

The St. Louis Cardinals (47-38) are coming off a dominant 7-0 victory over the Cleveland Guardians, while the Pittsburgh Pirates (35-50) crushed the New York Mets 12-1 in their last outing. Both teams enter this matchup with momentum, but the Cardinals have been the more consistent team this season. St. Louis is looking to solidify their position in the playoff race, while Pittsburgh aims to build on their recent offensive explosion.

Historic Head-to-Head Stats and Analysis

In their last 13 meetings, the Cardinals have dominated with a 10-3 record against the Pirates. St. Louis has also been strong on the road, winning 5 of their last 7 away games. Meanwhile, Pittsburgh has shown some resilience recently, going 5-2 in their last 7 games overall. However, the Cardinals' superior form and head-to-head success make them the favorites in this matchup.

Pick: St. Louis Cardinals Moneyline (-125)

widget-odds-mlb-su-11377-STL-PIT

The Cardinals have been the more reliable team this season, and their recent head-to-head dominance over the Pirates gives them the edge. With Andre Pallante (5-4, 4.43 ERA) on the mound for St. Louis and Paul Skenes (4-7, 2.12 ERA) pitching for Pittsburgh, the Cardinals' offense should be able to provide enough run support to secure the win. Backing the Cardinals on the moneyline at -125 offers solid value.

Top Player Prop Picks

1. Paul Skenes Over 6.5 Strikeouts (-110)

Paul Skenes has been a strikeout machine this season, and with the Cardinals' lineup prone to strikeouts against right-handed pitchers, this line is achievable. Skenes has consistently hit this mark in recent starts, making this a strong prop bet.

2. Nolan Arenado Over 1.5 Total Bases (+120)

widget-props-mlb-11377-5758122

Arenado has been a key contributor for the Cardinals, and his ability to hit for extra bases makes this prop appealing. Against a young pitcher like Skenes, Arenado's experience and power could lead to multiple hits or an extra-base knock.

3. Bryan Reynolds Over 0.5 RBIs (+140)

widget-props-mlb-11377-5758275

Reynolds has been one of Pittsburgh's most consistent hitters, and with the Pirates' offense showing signs of life, he is a good bet to drive in at least one run. Look for Reynolds to capitalize on any scoring opportunities against Pallante.

New customer offers and more lines available at:

Free Picks available for new customers at: