St. Louis Cardinals @ Cincinnati Reds Player Props, Picks and Predictions - 4/28/2025 6:40 PM EDT

We have your St. Louis Cardinals @ Cincinnati Reds prop betting and game preview needs covered as the Cincinnati Reds host the St. Louis Cardinals in what promises to be an exciting matchup.

St. Louis Cardinals @ Cincinnati Reds Pick

Best Moneyline Odds: Reds -120, Cardinals +100
Best Total Odds: Over 9 (+105), Under 9 (-125)

Game Info

Date: April 28, 2025
Time: 6:40 PM EDT
Location: Great American Ball Park, Cincinnati, OH
TV: -

St. Louis Cardinals @ Cincinnati Reds Preview

The Cincinnati Reds come into this game with momentum, having won 4 of their last 5 games, including a dominant 8-1 victory over the Colorado Rockies in their previous outing. Meanwhile, the St. Louis Cardinals are struggling, losing 7 of their last 8 games, including a 7-1 defeat to the Milwaukee Brewers. The Reds are slight favorites in this matchup, and their recent form suggests they have the upper hand.

Historic Head-to-Head Stats and Analysis

In their last 5 meetings, the Reds hold a slight edge with a 3-2 record against the Cardinals. The Reds have also been strong at home, winning 60% of their games as moneyline favorites this season. On the other hand, the Cardinals have struggled on the road, going 1-7 in their last 8 away games. This head-to-head history and recent trends favor the Reds in this matchup.

Pick: Reds Moneyline (-120)

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The Reds are the pick here based on their recent form and home-field advantage. With the Cardinals struggling on the road and the Reds riding a wave of confidence, Cincinnati is well-positioned to secure the win. The moneyline at -120 offers solid value for bettors.

Top Player Prop Picks

1. Over 1.5 Total Bases for Jonathan India (+120)

Jonathan India has been a key contributor for the Reds, and his ability to get on base and hit for power makes this prop appealing. With the Cardinals' pitching staff struggling, India is in a good spot to exceed this line.

2. Over 0.5 RBIs for Joey Votto (+140)

Joey Votto remains a reliable run producer for the Reds. Facing a Cardinals team that has allowed plenty of runs recently, Votto has a strong chance to drive in at least one run in this game.

3. Over 4.5 Strikeouts for Reds Starting Pitcher (-)

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The Reds' starting pitcher has a favorable matchup against a Cardinals lineup that has struggled offensively. Expect him to rack up at least 5 strikeouts in this game.