San Diego Padres @ New York Yankees Player Props, Picks and Predictions - 5/5/2025 7:05 PM EDT

We have your San Diego Padres @ New York Yankees prop betting and game preview needs covered as the New York Yankees host the San Diego Padres in what promises to be an exciting matchup.

San Diego Padres @ New York Yankees Pick

Best Moneyline Odds: Yankees -150, Padres +125 (Check Odds).
Best Spread Odds: Padres +1.5 (-170), Yankees -1.5 (+150) (Check Odds).
Best Total Odds: Over 7.5 (-120), Under 7.5 (+100) (Check Odds).

Game Info

Date: May 5, 2025
Time: 7:05 PM EDT
Location: Yankee Stadium, New York, NY
TV: -

San Diego Padres @ New York Yankees Preview

The Yankees come into this game after a tough loss to the Tampa Bay Rays, while the Padres are riding high off a shutout victory against the Pittsburgh Pirates. Both teams are looking to gain momentum as they continue their respective campaigns. The Yankees have been strong at home, boasting a solid record as favorites, while the Padres have shown resilience on the road, particularly in underdog situations. This game will likely hinge on pitching matchups and timely hitting, with both teams having the firepower to make a statement.

Historic Head-to-Head Stats and Analysis

In their last 10 meetings, the Yankees have a slight edge over the Padres, winning 6 of those matchups. However, the Padres have been competitive, with several games decided by one run. The Yankees have historically performed well at home against the Padres, leveraging their home-field advantage. Meanwhile, the Padres have shown they can compete with strong pitching performances and clutch hitting in these encounters.

Pick: Yankees Moneyline (-150)

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The Yankees are the pick here on the moneyline. Despite their recent loss, they have been consistent at home and have a strong record as favorites. The Padres, while coming off a win, face a tougher challenge against a Yankees team that thrives in their home ballpark. Expect the Yankees to bounce back and secure the victory.

Top Player Prop Picks

1. Aaron Judge Over 1.5 Total Bases (+120)

Aaron Judge has been a force at Yankee Stadium, consistently delivering extra-base hits. Against the Padres' pitching staff, Judge's power and ability to find gaps make this a strong play.

2. Juan Soto Over 0.5 Home Runs (+400)

Juan Soto has been heating up at the plate and has the ability to take advantage of Yankee Stadium's short porch in right field. At +400, this is a high-value prop for a player with elite power.

3. Gerrit Cole Over 7.5 Strikeouts (-110)

Gerrit Cole has been dominant on the mound, especially at home. Facing a Padres lineup that has shown vulnerability to strikeouts, Cole is poised to rack up Ks in this matchup.

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