San Diego Padres @ Miami Marlins Player Props, Picks and Predictions - 7/22/2025 6:40 PM EDT

We have your San Diego Padres @ Miami Marlins prop betting and game preview needs covered as the San Diego Padres hit the road to face the Miami Marlins.

San Diego Padres @ Miami Marlins Pick

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Game Info

Date: 2025-07-22
Time: 6:40 PM EDT
Location: LoanDepot Park, Miami, Florida
TV: -

San Diego Padres @ Miami Marlins Preview

The San Diego Padres (24-27 on the road) are set to face the Miami Marlins (22-29 at home) in what promises to be an intriguing matchup. The Marlins are coming off two consecutive losses, while the Padres recently secured a road win. Miami's offense has been hitting well, averaging 8.7 hits per game. However, their bullpen ERA stands at 4.57, which is nearly a full run worse than San Diego's bullpen ERA of 3.61. The Marlins will be starting Cabrera, who will look to turn their recent fortunes around. The Padres have shown resilience on the road, but have also lost eight of their last nine games following a road win, a trend they'll be eager to reverse.

Historic Head-to-Head Stats and Analysis

Historically, the San Diego Padres have held an advantage over the Miami Marlins in head-to-head contests. The Padres boast 39 wins in their all-time series against the Marlins, including 14 victories achieved on the road in Miami. The Marlins, on the other hand, have secured 30 wins in head-to-head clashes, with 14 of those victories coming at their home ballpark. More recently, San Diego has been particularly dominant, winning 8 of their last 11 games against Miami straight up. Furthermore, the Padres have an impressive record of 4 wins in their last 5 games played in Miami. The Marlins have shown some strength against National League West opponents, winning six of their last seven games against teams from that division.

Pick: San Diego Padres Moneyline

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Considering the historical head-to-head dominance of the San Diego Padres over the Miami Marlins, especially when playing in Miami, the Padres moneyline presents a compelling pick. San Diego has won 8 of their last 11 overall against the Marlins and 4 of their last 5 games played in Miami. While the Marlins are starting Cabrera and have a decent home record, their recent two-game losing streak and a 30% win rate when favored this season raise concerns. The Padres also hold a significant advantage in bullpen ERA (3.61 at 4.57), which could be crucial in a close game. Despite the Padres' recent trend of losing after a road win, their strong historical performance against Miami, coupled with a better bullpen, makes them the favored side in this matchup.

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