Los Angeles Chargers at Arizona Cardinals Player Props, Picks and Predictions - 10/21/2024 9:00 PM EST

We have your Los Angeles Chargers at Arizona Cardinals prop betting and game preview needs covered as the Los Angeles Chargers hit the road to face the Arizona Cardinals.

Los Angeles Chargers at Arizona Cardinals Odds Info

Best Moneyline Odds: Los Angeles Chargers -135 (DraftKings) / Arizona Cardinals +120 (BetMGM)
Best Spread Odds: 2.5 - Los Angeles Chargers -115 (Caesars) / Arizona Cardinals -105 (Caesars)
Best Total Odds: 43.5 - Under -110 (Caesars) / Over -110 (bet365)

Game Info

Date: 10/21/2024
Time: 9:00 PM EST
Location: State Farm Stadium (Glendale, AZ)
TV: ESPN+

Historic Head-to-Head Stats and Analysis

In the past three seasons, the Los Angeles Chargers and the Arizona Cardinals have faced each other once, with the Chargers emerging victorious. This matchup took place on November 27, 2022, where the Chargers, as the visiting team, secured a narrow 25-24 win over the Cardinals. The Chargers were favored to win, as indicated by the closing spread of 2.5 points in their favor, yet they did not cover the spread, with the Cardinals winning against the spread. The game saw a total score of 49 points, surpassing the closing over-under line of 48.5, resulting in the game going over. This single encounter provides a limited but insightful look into the dynamics between these two teams, with the Chargers holding the upper hand in terms of victories.

In the detailed account of their most recent game, the Chargers managed to clinch a win with a decisive play in the fourth quarter. The game began with the Cardinals taking an early lead, thanks to a 33-yard touchdown pass from Kyler Murray to DeAndre Hopkins and a 43-yard field goal by Matt Prater, putting them ahead 10-0. The Chargers responded with two touchdown passes from Justin Herbert, one to Keenan Allen and another to DeAndre Carter, taking a 14-10 lead. However, a 5-yard rushing touchdown by Murray just before halftime gave the Cardinals a 17-14 advantage. In the second half, the Chargers tied the game with a field goal, but the Cardinals regained the lead with a touchdown pass to James Conner. The Chargers ultimately secured the win with a 1-yard touchdown pass to Austin Ekeler, followed by a successful two-point conversion.

Statistically, the Chargers accumulated 311 total yards, with 246 of those coming through the air and 65 on the ground. They completed 35 of 47 passing attempts, resulting in three passing touchdowns and no interceptions. The Cardinals, on the other hand, amassed 366 total yards, with a balanced attack of 185 passing yards and 181 rushing yards. They completed 18 of 29 passing attempts, with two passing touchdowns and one interception. Both teams committed two turnovers, but the Chargers managed to avoid any in the second half, which proved crucial in their comeback victory. The Chargers' defense recorded one sack and one interception, while the Cardinals' defense managed four sacks. Penalties were minimal, with the Chargers incurring 30 penalty yards and the Cardinals 19.

Los Angeles Chargers at Arizona Cardinals Preview

The Los Angeles Chargers and Arizona Cardinals are set to clash in a pivotal Week 7 matchup that promises to be a compelling contest. The Chargers, under the guidance of head coach Jim Harbaugh, have shown significant improvement this season, boasting a 3-2 record. Their recent victory over the Denver Broncos marked a turning point, as they snapped a two-game losing streak with a balanced offensive attack and a staunch defensive performance. Justin Herbert, the Chargers' quarterback, has been instrumental in this resurgence, delivering a solid performance against Denver with 237 passing yards, a marked improvement from his earlier season averages.

On the other side, the Arizona Cardinals are grappling with inconsistency, holding a 2-4 record. Their recent defeat to the Green Bay Packers was a stark reminder of their vulnerabilities, particularly on defense, where they allowed four touchdown passes and committed three turnovers. The Cardinals' defense, ranked last in third-down efficiency, will face a formidable challenge against a Chargers team that excels in controlling the game tempo and limiting opponents' scoring opportunities.

Despite their struggles, the Cardinals have shown flashes of potential, particularly in their upset victory over the San Francisco 49ers earlier in the season. Kyler Murray, known for his dynamic playmaking ability, will be crucial to Arizona's hopes of securing a win. However, the absence of key players like Marvin Harrison Jr., who is sidelined with a concussion, could hinder their offensive output. The Cardinals' rushing attack, which ranks third in the league, will need to be at its best to counter the Chargers' top-ranked scoring defense.

This matchup is further complicated by the Chargers' own injury concerns, notably the potential absence of tight end Hayden Hurst due to a groin injury. Nevertheless, the Chargers have demonstrated resilience, with their defense leading the league in points allowed and their offense finding ways to adapt and overcome challenges. As both teams vie for a crucial win, the game is poised to be a high-stakes encounter with significant implications for their respective seasons.

Los Angeles Chargers at Arizona Cardinals Pick: Total Points Over

The upcoming clash between the Los Angeles Chargers and the Arizona Cardinals is shaping up to be a high-scoring affair, making the over on the total points a compelling pick. The Chargers, under the leadership of head coach Jim Harbaugh, have shown a marked improvement in their offensive capabilities, particularly after their recent victory over the Denver Broncos. Justin Herbert's resurgence, highlighted by his 237 passing yards against Denver, signals a more balanced offensive approach that could exploit the Cardinals' defensive vulnerabilities.

Arizona's defense has struggled significantly, particularly in recent weeks, as evidenced by their performance against the Green Bay Packers, where they allowed four touchdown passes and committed three turnovers. The Cardinals' defense ranks last in third-down efficiency, a critical weakness that the Chargers' offense, which excels in controlling the game tempo, is likely to exploit. Furthermore, the Cardinals have allowed an average of 153 rushing yards per game, ranking 29th in the league, which could open up opportunities for the Chargers' running game to contribute to the scoring.

On the offensive side, the Cardinals have shown potential, particularly with Kyler Murray's dynamic playmaking ability. Despite the absence of key players like Marvin Harrison Jr., the Cardinals' offense has the capability to put points on the board, especially given their third-ranked rushing attack. Murray's ability to extend plays and scramble for first downs adds an unpredictable element that could challenge the Chargers' defense, which, while top-ranked in scoring, has faced relatively average passing offenses this season.

Moreover, the Chargers' defense, despite its strengths, has been average against the pass, and facing a quarterback of Murray's caliber could lead to a higher-scoring game. The Cardinals' motivation to bounce back from their recent loss and the Chargers' need to maintain their momentum further suggest a competitive and high-scoring matchup. With both teams having the potential to exploit each other's defensive weaknesses, the over on the total points is a strong pick for this Monday night showdown.

Los Angeles Chargers at Arizona Cardinals Top Player Prop Picks

Justin Herbert Over 237.5 Passing Yards - Passing Yards Prop -110 (DraftKings)

Justin Herbert's recent performance against the Denver Broncos, where he threw for 237 yards, indicates a resurgence in his passing game. The Chargers have shown a more balanced offensive approach, which could exploit the Cardinals' defensive weaknesses. Arizona's defense has struggled significantly, particularly in recent weeks, allowing four touchdown passes against the Packers and ranking last in third-down efficiency. This vulnerability presents a prime opportunity for Herbert to exceed the 237.5 passing yards mark, especially given the Cardinals' defensive struggles against the pass.

Kyler Murray Over 1.5 Passing Touchdowns - Passing Touchdowns Prop +120 (BetMGM)

Kyler Murray's dynamic playmaking ability is crucial for the Cardinals, especially in a game where they need to bounce back from a disappointing loss. Despite the absence of key players like Marvin Harrison Jr., Murray's ability to extend plays and find the end zone remains a constant threat. The Chargers' defense, while top-ranked in scoring, has faced relatively average passing offenses this season, and Murray's unique skill set could lead to multiple passing touchdowns. With the Cardinals' offense needing to keep pace with the Chargers, Murray is likely to surpass the 1.5 passing touchdowns line.

J.K. Dobbins Over 65.5 Rushing Yards - Rushing Yards Prop -105 (Caesars)

The Chargers' running game has been a significant factor in their offensive strategy, particularly after their bye week. J.K. Dobbins, alongside Kimani Vidal, combined for 153 scrimmage yards against Denver, showcasing their ability to dominate on the ground. The Cardinals' defense, allowing an average of 153 rushing yards per game and ranking 29th in the league, presents a favorable matchup for Dobbins. With the Chargers likely to exploit this weakness, Dobbins is well-positioned to exceed the 65.5 rushing yards mark, contributing significantly to the Chargers' offensive output.