Houston Astros @ St. Louis Cardinals Player Props, Picks and Predictions - 4/14/2025 7:45 PM EDT

We have your Houston Astros @ St. Louis Cardinals prop betting and game preview needs covered as the St. Louis Cardinals host the Houston Astros in what promises to be an exciting matchup.

Houston Astros @ St. Louis Cardinals Pick

Best Moneyline Odds: Astros -118 (Bet Now)
Best Spread Odds: Astros -1.5 (+145) (Bet Now)
Best Total Odds: Over 7.0 (-110) (Bet Now)

Game Info

Date: April 14, 2025
Time: 7:45 PM EDT
Location: Busch Stadium III, St. Louis, MO
TV: -

Houston Astros @ St. Louis Cardinals Preview

The Houston Astros come into this game fresh off a 7-3 victory over the Los Angeles Angels, showcasing their offensive firepower. Meanwhile, the St. Louis Cardinals are riding high after a dominant 7-0 shutout win against the Philadelphia Phillies. Both teams are looking to build momentum, with the Astros relying on their ace Framber Valdez to neutralize the Cardinals' lineup. The Cardinals, on the other hand, will aim to capitalize on their home-field advantage and continue their recent offensive surge.

Historic Head-to-Head Stats and Analysis

In their last 10 meetings, the Houston Astros have held a slight edge over the St. Louis Cardinals, winning 6 of those matchups. The Astros have consistently performed well on the road against the Cardinals, leveraging their strong pitching and timely hitting. However, the Cardinals have shown resilience, particularly in close games, making this matchup a compelling one to watch.

Pick: Astros Moneyline (-118)

widget-odds-mlb-su-10356-HOU-STL

The Astros are slight favorites in this matchup, and for good reason. With Framber Valdez on the mound, Houston has a reliable ace who can stifle the Cardinals' offense. Additionally, the Astros' recent offensive output gives them the edge in this contest. While the Cardinals are coming off a strong performance, their inconsistency this month makes the Astros the safer pick.

Top Player Prop Picks

1. Framber Valdez Over 6.5 Strikeouts (-110)

widget-props-mlb-10356-4928318

Valdez has been dominant this season, consistently racking up strikeouts. Against a Cardinals lineup that has struggled against left-handed pitching, Valdez is poised to surpass this line.

2. Yordan Alvarez Over 1.5 Total Bases (+120)

widget-props-mlb-10356-4928327

Alvarez has been a key contributor for the Astros, and his power at the plate makes this a strong value pick. Look for him to take advantage of favorable matchups in the Cardinals' pitching staff.

3. Paul Goldschmidt Over 0.5 Home Runs (+400)

Goldschmidt remains a threat in the Cardinals' lineup, and his ability to hit for power at home makes this a high-upside prop bet. If the Cardinals are to compete, Goldschmidt will need to deliver.

Free Picks available for new customers at: