Detroit Tigers @ St. Louis Cardinals Player Props, Picks and Predictions - 5/19/2025 7:45 PM EDT

We have your Detroit Tigers @ St. Louis Cardinals prop betting and game preview needs covered as the St. Louis Cardinals hit the road to face the Detroit Tigers.

Detroit Tigers @ St. Louis Cardinals Pick

Best Moneyline Odds: St. Louis Cardinals -160, Detroit Tigers +135 (Bet Now).
Best Total Odds: Over/Under 8.5 runs (Bet Now).

Game Info

Date: May 19, 2025
Time: 7:45 PM EDT
Location: Busch Stadium, St. Louis, MO
TV: -

Detroit Tigers @ St. Louis Cardinals Preview

The Detroit Tigers and St. Louis Cardinals square off in what promises to be an exciting interleague matchup. The Tigers are coming off a narrow 3-2 victory over the Toronto Blue Jays, while the Cardinals dropped a close 2-1 game to the Kansas City Royals. Both teams will be looking to bounce back and gain momentum in this series opener. The Cardinals, with a 26-21 record, have been solid this season but will need to capitalize on their home-field advantage to fend off a scrappy Tigers team.

Historic Head-to-Head Stats and Analysis

In their recent head-to-head matchups, the Tigers and Cardinals have been evenly matched, with both teams trading wins. The Tigers secured a 2-1 victory in their last meeting on May 18, 2025, showcasing their ability to compete against a strong Cardinals lineup. Historically, the Cardinals have a slight edge in interleague play, but the Tigers have proven to be a tough opponent, especially in close games.

Pick: St. Louis Cardinals Moneyline (-160)

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The Cardinals are the favorites in this matchup, and for good reason. Despite their recent loss, they have been consistent at home and boast a strong lineup capable of putting up runs. The Tigers, while competitive, have struggled as road underdogs, making the Cardinals a solid pick to win outright. Backing the Cardinals on the moneyline at -160 offers a reasonable value for bettors.

Top Player Prop Picks

1. Brendan Donovan Over 1.5 Total Bases

Donovan has been a key contributor for the Cardinals, coming off a four-hit performance in his last game. With his ability to make consistent contact and drive the ball, he is a strong candidate to exceed 1.5 total bases in this matchup.

2. Spencer Torkelson Over 0.5 Home Runs

Torkelson has shown flashes of power this season and could take advantage of a favorable pitching matchup. Betting on him to hit a home run offers great value for those looking for a high-reward prop.

3. Matthew Boyd Over 5.5 Strikeouts

Boyd has been a strikeout machine for the Tigers, and the Cardinals' lineup has shown vulnerability to strikeouts in recent games. Expect Boyd to rack up at least six strikeouts in this contest.

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