Colorado Rockies @ St. Louis Cardinals Player Props, Picks and Predictions - 8/12/2025 7:45 PM EDT

We have your Colorado Rockies @ St. Louis Cardinals prop betting and game preview needs covered as the Colorado Rockies hit the road to face the St. Louis Cardinals.

Colorado Rockies @ St. Louis Cardinals Pick

Best Moneyline Odds: St. Louis Cardinals -184 (FanDuel) / Colorado Rockies +158 (Caesars)
Best Spread Odds: St. Louis Cardinals -1.5 (-130) (Caesars)
Best Total Odds: Over 8.5 (-105) (Caesars) / Under 8.5 (-106) (BetRivers)

Game Info

Date: 2025-08-12
Time: 7:45 PM EDT
Location: Busch Stadium
TV: -

Colorado Rockies @ St. Louis Cardinals Preview

The St. Louis Cardinals are set to host the Colorado Rockies at Busch Stadium tonight, entering the game as significant favorites after securing a win in their series opener on Monday. The Rockies are currently on a prolonged losing streak and will be looking to turn their fortunes around in this matchup.

The pitching matchup heavily favors the Cardinals. Matthew Liberatore, the Cardinals' starter, has had a solid season with a 3.98 ERA and a 1.29 WHIP, effectively limiting walks and long balls. In contrast, Colorado's Kyle Freeland has struggled significantly in 2025, holding a 2-12 record with a high 5.53 ERA and a bloated 1.52 WHIP.

The Cardinals appear to hold all the advantages in this contest, boasting superior pitching, a stronger offensive lineup, and a favorable home record against the Rockies. The Rockies' current pitching and offensive deficiencies are quite evident, especially with a lengthy injury list that includes Germán Márquez, Angel Chivilli, Thairo Estrada, Orlando Arcia, Ryan Ritter, Seth Halvorsen, Antonio Senzatela, Zach Agnos, Kris Bryant, Case Williams, and Jeff Criswell.

Historic Head-to-Head Stats and Analysis

The season series between the Colorado Rockies and St. Louis Cardinals is currently tied at 2-2. Historically, the Rockies have shown a peculiar trend, winning four of their last five games as road underdogs against the Cardinals following a loss. Additionally, the last two games played between these two teams have gone under their respective totals.

Pick: St. Louis Cardinals Moneyline

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The St. Louis Cardinals are the clear pick for this game. Their starting pitcher, Matthew Liberatore, has been far more effective than Colorado's Kyle Freeland, who has struggled considerably this season. The Cardinals also possess a stronger overall lineup and the advantage of playing at home. Sharp betting data indicates a 62.14% sharp win percentage for the Cardinals on the moneyline, reinforcing their strong position in this matchup. While the Rockies have a historical trend of performing well as road underdogs against the Cardinals after a loss, the current form and significant pitching mismatch strongly point towards a Cardinals victory.

Top Player Prop Picks

Willson Contreras Over 1.5 Total Bases

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Despite a challenging historical individual matchup against Kyle Freeland, where Willson Contreras is 0-for-10 with 4 strikeouts, the overall context of this game suggests an opportunity for him. Freeland has a high 5.53 ERA and 1.52 WHIP this season, indicating he gives up a lot of hits. Contreras has a solid season slugging percentage of 0.447, and the Cardinals' offense is expected to perform well against Freeland's struggles. This pick aligns with the general expectation of a strong offensive performance from the Cardinals.

Alec Burleson Over 0.5 Home Runs

This prop pick is based on the expectation that Alec Burleson can capitalize on Kyle Freeland's struggles. While Busch Stadium has a slightly pitcher-friendly home run park factor of 89, Freeland's high ERA and WHIP suggest he is vulnerable to giving up extra-base hits. Burleson holds a 3.4% home run rate this season. Although there are no specific career head-to-head stats for Burleson against Freeland in the provided research, the overall weakness of Freeland's pitching could present an opportunity for Burleson to connect for a long ball.

Matthew Liberatore Over 5.5 Strikeouts

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Matthew Liberatore is in a favorable position to exceed 5.5 strikeouts against the Colorado Rockies. Liberatore has maintained a respectable 3.98 ERA and 1.29 WHIP this season. The Rockies' lineup features several players with high strikeout rates, including Hunter Goodman (26.1% K%), Jordan Beck (27.9% K%), Mickey Moniak (25.1% K%), and Brenton Doyle (25.7% K%). These high strikeout percentages among key Rockies hitters provide a strong statistical basis for Liberatore to achieve over 5.5 strikeouts in this outing.

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