Cleveland Guardians @ Washington Nationals Player Props, Picks and Predictions - 5/5/2025 6:45 PM EDT

We have your Cleveland Guardians @ Washington Nationals prop betting and game preview needs covered as the Washington Nationals hit the road to face the Cleveland Guardians.

Cleveland Guardians @ Washington Nationals Pick

Best Moneyline Odds: Cleveland Guardians -113, Washington Nationals +105.
Best Spread Odds: Guardians -1.5 (+145), Nationals +1.5 (-154).
Best Total Odds: Over 9 (-110), Under 9 (-110).

Game Info

Date: May 5, 2025
Time: 6:45 PM EDT
Location: Progressive Field, Cleveland, OH
TV: -

Cleveland Guardians @ Washington Nationals Preview

The Cleveland Guardians come into this matchup after a thrilling 5-4 victory over the Toronto Blue Jays, showcasing their ability to win close games. Meanwhile, the Washington Nationals are riding high after a 4-1 win against the Cincinnati Reds, demonstrating solid pitching and timely hitting. Both teams are looking to build momentum as they face off in this interleague clash.

Historic Head-to-Head Stats and Analysis

In their recent head-to-head matchups, the Cleveland Guardians have had the upper hand, winning 4 of the last 6 games against the Washington Nationals. The Guardians have consistently outperformed the Nationals in terms of pitching, holding Washington to an average of 3.2 runs per game during this span. On the other hand, the Nationals have struggled to generate offense against Cleveland's strong rotation, which could be a key factor in this game.

Pick: Cleveland Guardians Moneyline (-113)

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The Cleveland Guardians are the pick on the moneyline due to their recent form and historical success against the Nationals. Cleveland has been dominant as a moneyline favorite, boasting a 10-2 record in such situations this season. Additionally, their ability to win close games, as evidenced by their victory over Toronto, gives them the edge in this matchup. The Nationals, while coming off a win, have struggled as underdogs, making Cleveland the safer pick.

Top Player Prop Picks

1. José Ramírez Over 1.5 Total Bases (+120)

José Ramírez has been a consistent offensive force for the Guardians, and his ability to hit for extra bases makes this prop appealing. Facing a Nationals pitching staff that has allowed a high slugging percentage to opposing hitters, Ramírez is well-positioned to exceed this line.

2. Josh Bell Over 0.5 RBIs (+140)

Josh Bell has been a key run producer for the Guardians, and with runners likely to be on base against a Nationals pitching staff that has struggled in high-leverage situations, Bell has a strong chance to drive in at least one run.

3. Patrick Corbin Under 4.5 Strikeouts (-110)

Patrick Corbin has struggled to miss bats this season, and the Guardians' lineup is one of the toughest in the league to strike out. This combination makes the under on Corbin's strikeout total a solid play.

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