Cincinnati Reds @ Washington Nationals Player Props, Picks and Predictions - 7/21/2025 6:45 PM EDT

We have your Cincinnati Reds @ Washington Nationals prop betting and game preview needs covered as the Cincinnati Reds hit the road to face the Washington Nationals.

Cincinnati Reds @ Washington Nationals Pick

Best Moneyline Odds: Cincinnati Reds -134, Washington Nationals +114
Best Spread Odds: Cincinnati Reds -1.5 (-110), Washington Nationals +1.5 (+112)

Game Info

Date: 7/21/2025
Time: 6:45 PM EDT
Location: Nationals Park, Washington, D.C.
TV: -

Cincinnati Reds @ Washington Nationals Preview

The Cincinnati Reds, with a season record of 52-48, head into Washington D.C. as the road favorites against the Washington Nationals (39-60). The Reds have shown solid recent form, winning 6 of their last 10 games and securing victories in 4 of their last 5 road contests. They've also been particularly effective when their bats are hot, boasting a 42-19 record this season when recording 8 or more hits in a game. However, their performance as moneyline favorites has been mixed, with a 22-21 record in 43 such games this season. Cincinnati is expected to start Brady Singer (7-7), who found significant consistency in June. The Washington Nationals, despite their overall record, have shown resilience, particularly against the Reds. They've won 34 of their 79 games as underdogs this season, representing a 43% win rate in those situations. The Nationals are projected to send Brad Lord (2-5, 3.46 ERA) to the mound.

Historic Head-to-Head Stats and Analysis

In recent years, the Washington Nationals have held an advantage in the head-to-head rivalry against the Cincinnati Reds, holding a 7-3 edge. This includes a recent 2-1 series victory over the Reds. Notably, the Nationals have demonstrated a pattern of success against Cincinnati, winning each of their last three games as underdogs against the Reds following a loss.

Pick: Washington Nationals Moneyline (+114)

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Despite the Cincinnati Reds being the road favorites, the Washington Nationals present a compelling value pick on the moneyline. The Nationals have historically performed well against the Reds, holding a 7-3 edge in recent head-to-head matchups, including a recent series win. More importantly for betting purposes, Washington has shown a knack for winning as underdogs against Cincinnati, particularly after a loss. This trend, combined with their home-field advantage and the favorable +114 odds, makes the Nationals moneyline an attractive play. While the Reds have a better overall record, the Nationals' specific success in this rivalry, especially in underdog scenarios, suggests they are undervalued in this matchup.

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