Chicago Cubs @ St. Louis Cardinals Player Props, Picks and Predictions - 6/23/2025 7:45 PM EDT

We have your Chicago Cubs @ St. Louis Cardinals prop betting and game preview needs covered as the Chicago Cubs hit the road to face the St. Louis Cardinals.

Chicago Cubs @ St. Louis Cardinals Pick

Best Moneyline Odds: -
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Game Info

Date: June 23, 2025
Time: 7:45 PM EDT
Location: Busch Stadium, St. Louis, MO
TV: -

Chicago Cubs @ St. Louis Cardinals Preview

The Chicago Cubs (46-31) travel to Busch Stadium to face their long-time rivals, the St. Louis Cardinals (42-36). Both teams are looking to gain ground in the competitive NL Central division. The Cubs are coming off a tough loss to the Seattle Mariners, while the Cardinals dropped their last game to the Cincinnati Reds. This matchup features two teams with playoff aspirations, and the intensity of this rivalry is sure to make for an exciting game.

Historic Head-to-Head Stats and Analysis

The Chicago Cubs and St. Louis Cardinals have a storied rivalry, with the Cardinals holding an all-time record of 1221-1273 against the Cubs. Over the last five years, the Cubs have had a slight edge in head-to-head matchups, going 14-12. In their most recent 10 meetings, the Cubs have won six games, while the Cardinals have taken four. This season, the Cubs have been strong as moneyline favorites, while the Cardinals have been competitive as underdogs.

Pick: Moneyline - Chicago Cubs

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The Cubs have been consistent this season, boasting a 46-31 record. With their strong lineup and recent success in head-to-head matchups, they are well-positioned to secure a win against the Cardinals. The Cardinals, while competitive, have struggled in recent games, making the Cubs a solid pick for the moneyline.

Top Player Prop Picks

1. Paul Goldschmidt - Over 0.5 Home Runs

Goldschmidt remains a threat in the Cardinals' lineup. With his power and ability to capitalize on mistakes, he is a good candidate to go deep in this matchup.

2. Justin Steele - Over 5.5 Strikeouts

Steele has been a reliable arm for the Cubs, and his ability to generate swings and misses makes this prop appealing. The Cardinals' lineup has shown vulnerability to strikeouts, which could work in Steele's favor.

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