Chicago Cubs @ Pittsburgh Pirates Player Props, Picks and Predictions - 5/1/2025 12:35 PM EDT

We have your Chicago Cubs @ Pittsburgh Pirates prop betting and game preview needs covered as the Pittsburgh Pirates hit the road to face the Chicago Cubs.

Chicago Cubs @ Pittsburgh Pirates Pick

Best Moneyline Odds: Pittsburgh Pirates -145, Chicago Cubs +118
Best Total Odds: Over/Under 7.5 (-110)

Game Info

Date: May 1, 2025
Time: 12:35 PM EDT
Location: Wrigley Field, Chicago, IL
TV: -

Chicago Cubs @ Pittsburgh Pirates Preview

The Chicago Cubs and Pittsburgh Pirates face off in the final game of their series at Wrigley Field. The Pirates secured a narrow 4-3 victory in the previous game, showcasing their ability to capitalize on key opportunities. The Cubs, on the other hand, will look to bounce back and even the series. Both teams have shown flashes of brilliance this season, but consistency remains a challenge. With the Pirates slightly favored, this matchup promises to be a competitive affair.

Historic Head-to-Head Stats and Analysis

In their last 10 meetings, the Pirates hold a slight edge with a 6-4 record against the Cubs. Notably, the Over has hit in 8 of the last 10 games played in Chicago, indicating a trend toward higher-scoring contests when these teams meet at Wrigley Field. The Cubs recently dominated the Pirates 9-0 on April 29, 2025, but the Pirates responded with a 4-3 win on April 30, 2025, showcasing the back-and-forth nature of this rivalry.

Pick: Over 7.5 (-110)

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The Over has been a consistent trend in this matchup, particularly at Wrigley Field. With 8 of the last 10 games in Chicago going Over, and both teams showing offensive potential in recent games, the Over 7.5 is a strong play. Additionally, the Pirates' recent offensive surge and the Cubs' ability to score in bunches make this total achievable.

Top Player Prop Picks

1. Bryan Reynolds Over 1.5 Total Bases (+120)

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Reynolds has been a key contributor for the Pirates, and his ability to hit for extra bases makes this prop appealing. With the Cubs' pitching staff struggling to contain him in recent matchups, Reynolds is poised for another productive game.

2. Cody Bellinger Over 0.5 Home Runs (+400)

Bellinger has shown power at the plate this season and has a favorable matchup against the Pirates' pitching staff. His ability to drive the ball out of Wrigley Field makes this a high-upside prop bet.

3. Justin Steele Over 5.5 Strikeouts (-110)

Steele has been a strikeout machine for the Cubs, and the Pirates' lineup has been prone to strikeouts in recent games. Look for Steele to rack up the Ks in this matchup.

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