Boston Red Sox @ Houston Astros Player Props, Picks and Predictions - 8/13/2025 7:10 PM EDT

We have your Boston Red Sox @ Houston Astros prop betting and game preview needs covered as the Boston Red Sox hit the road to face the Houston Astros.

Boston Red Sox @ Houston Astros Pick

Best Moneyline Odds: Houston Astros -150 [BetMGM] | Boston Red Sox +143 [BetRivers]
Best Spread Odds: Houston Astros -1.0 (-111) [DraftKings]
Best Total Odds: Over 7.5 (-125) [ESPN BET] | Under 8.0 (-109) [BetRivers]

Game Info

Date: August 13, 2025
Time: 7:10 PM EDT
Location: Daikin Park, Houston, TX
TV: SCHN

Boston Red Sox @ Houston Astros Preview

The Boston Red Sox (65-55) travel to Daikin Park to take on the Houston Astros (67-52) in what promises to be an engaging MLB matchup. The Red Sox, currently second in the AL East, are looking to build on their recent dominant 14-1 road victory over the Astros, which snapped a three-game losing streak. The Astros, leading the AL West, will be eager to bounce back from that significant loss and continue their strong season at home.

On the mound, the Red Sox will send right-hander Dustin May (6-8, 4.93 ERA) to start. May is making just his second start since being acquired by Boston at the trade deadline and struggled in his debut, allowing three runs on six hits over 3.2 innings. Over his last seven starts overall, he holds a 3-3 record with a 5.54 ERA. His lone career start against the Astros came in 2020, where he allowed one run over 3.1 innings.

For the Houston Astros, right-hander Hunter Brown (9-5, 2.51 ERA) will take the hill. Brown has been a key pitcher for the Astros this season, boasting a significantly lower ERA than his counterpart. When Brown starts, his team has a 13-10 record against the spread and an 11-7 record when they are moneyline favorites.

Offensively, the Red Sox possess a potent lineup, ranking 5th in slugging percentage (.429) and leading the league in doubles (247). They demonstrated their power in the recent 14-1 win, and even in a prior 7-6 loss, they managed 10 hits and 3 home runs, with Roman Anthony and Alex Bregman contributing long balls. The Astros' offense is equally formidable, ranking second in the league with a .259 batting average. They showed their depth in a recent 7-6 win over Boston, with Ramón Urías hitting a home run and driving in two RBIs, and trade deadline additions like Carlos Correa and Jesus Sanchez making immediate impacts. The Astros' pitching staff is also a strength, ranking third in batting average against (.230) and seventh in ERA (3.71).

Both teams are dealing with injuries. The Red Sox are without Marcelo Mayer (10-Day-IL), and several players including Justin Slaten, Luis Guerrero, Tanner Houck, Hunter Dobbins, Patrick Sandoval, Josh Winckowski, Liam Hendriks, and Triston Casas are on the 60-Day-IL. Mark Kolozsvary is day-to-day, and Roman Anthony is out. For the Astros, key hitters Yordan Alvarez and Jake Meyers are out, along with several pitchers like Josh Hader (15-Day-IL), J.P. France, Luis Garcia, and Lance McCullers Jr. (all 60-Day-IL or 15-Day-IL). Glenn Otto is day-to-day.

Historic Head-to-Head Stats and Analysis

The Boston Red Sox and Houston Astros have a rich history of competitive matchups. Their most recent encounter on August 12, 2025, saw the Red Sox secure a decisive 14-1 victory on the road. Prior to that, the Astros edged out the Red Sox 7-6 on August 11, 2025. Looking further back, the Red Sox had a strong run against the Astros earlier in August, winning 6-1 on August 3rd, 7-3 on August 2nd, and 2-1 on August 1st.

Overall, the Houston Astros hold a slight edge in total victories with 43 wins (22 at home) compared to the Boston Red Sox's 39 wins (20 on the road). The Astros average 5 runs per game in head-to-head contests, while the Red Sox average 4.78 runs. Boston has historically performed well on the road against Houston, often exceeding the 3.5-run mark. In their last 10 head-to-head games, the Red Sox have a 6-4 record against the Over/Under, while the Astros are 5-5. Over the last 3 games, both teams have a 2-1 record against the Over/Under.

Pick: Houston Astros Moneyline

Despite the Boston Red Sox's commanding 14-1 victory yesterday, the Houston Astros are positioned well for a bounce-back win at home. The Astros are favored by sharp money, with a 59.14% sharp win probability on the moneyline. Furthermore, a predictive model gives the Astros a 64.1% chance of winning this game. The pitching matchup heavily favors Houston, with Hunter Brown (2.51 ERA) taking the mound against Dustin May (4.93 ERA). Brown's strong performance this season, coupled with his team's solid record when he starts, provides a significant advantage. While the Red Sox offense has shown flashes of brilliance, the Astros' overall pitching strength and home-field advantage should allow them to secure the victory.

Top Player Prop Picks

Carlos Correa (Houston Astros) Over 0.5 Hits

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Carlos Correa has historically performed exceptionally well against Red Sox starter Walker Buehler. In 8 career plate appearances against Buehler, Correa boasts a .429 batting average with 3 hits, including a home run, and an impressive .857 slugging percentage. His wOBA against Buehler stands at .555. Coming off a key RBI single in the last game, Correa is in good form and poised to continue his success against this particular pitcher.

Christian Walker (Houston Astros) Over 0.5 Home Run

Christian Walker has demonstrated significant power against Walker Buehler in their career matchups. In 29 plate appearances, Walker has hit 3 home runs, resulting in a .556 slugging percentage and a .343 wOBA against Buehler. This high home run rate suggests a strong likelihood of him going deep again in this matchup.

Alex Bregman (Boston Red Sox) Over 0.5 Hits

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Alex Bregman, returning to his former home ballpark, has shown excellent recent form and strong historical numbers against Astros starter Hunter Brown. In the last game, Bregman went 2-for-4 with a home run. Against Hunter Brown, he has a perfect 2-for-3 record in his career, with a .667 batting average and .667 slugging percentage. His comfort at Minute Maid Park and his success against Brown make him a strong candidate to record a hit.

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