Boston Red Sox @ Baltimore Orioles Player Props, Picks and Predictions - 8/27/2025 6:35 PM EDT

We have your Boston Red Sox @ Baltimore Orioles prop betting and game preview needs covered as the Boston Red Sox hit the road to face the Baltimore Orioles.

Boston Red Sox @ Baltimore Orioles Pick

Best Moneyline Odds: Boston Red Sox -135 on ESPN BET / Baltimore Orioles +120 on Fanduel
Best Spread Odds: Boston Red Sox -1.0 (-114) on BetRivers / Baltimore Orioles +1.5 (-134) on Fanduel
Best Total Odds: Over 8.5 (-135) on ESPN BET / Under 9.0 (-104) on BetRivers

Game Info

Date: 2025-08-27
Time: 6:35 PM EDT
Location: Oriole Park at Camden Yards
TV: -

Boston Red Sox @ Baltimore Orioles Preview

The Boston Red Sox (73-60) head to Oriole Park at Camden Yards to face the Baltimore Orioles (60-71) in what shapes up to be a crucial AL East matchup. The Red Sox are currently surging, holding a 73-60 record this season and showing strong form with a 6-4 record in their last 10 games. Their offense has been productive, averaging 5.29 runs per game, and their pitching staff boasts a solid 3.26 ERA with a 9.1 K/9 rate. Boston will send right-hander Brayan Bello to the mound, who holds a 10-6 record with a 3.07 ERA and 102 strikeouts this season. Bello has been particularly effective against the Orioles, going 3-1 with a 3.16 ERA and 28 strikeouts in his last five starts against them. The Red Sox bullpen is also a significant strength, featuring closer Aroldis Chapman (1.06 ERA, 25 saves) and a deep supporting cast that is well-rested after their last game.

On the other side, the Baltimore Orioles are navigating a challenging stretch, sitting at 60-71 this season and having gone 4-6 in their last 10 outings. Their offense averages 4.32 runs per game, while their pitching staff has a 4.11 ERA. The Orioles will counter with left-hander Dietrich Enns, who has a 1-2 record with a 4.97 ERA and 32 strikeouts this season. Baltimore's bullpen has been impacted by injuries and trades, relying heavily on Felix Bautista (19 saves) but lacking overall depth. Key players like Adley Rutschman and Tyler O'Neill are currently sidelined due to injury, further impacting the Orioles' lineup.

Camden Yards, once known as a hitter's paradise, has transformed into a more pitcher-friendly venue since the left field wall was adjusted in 2022. It now ranks 22nd in runs factor (0.938) and home run factor (0.908), which could benefit a ground ball pitcher like Bello.

Historic Head-to-Head Stats and Analysis

The Boston Red Sox have taken the first two games of this series, securing victories by scores of 4-3 and 5-0, including a dominant 5-0 win on August 26, 2025. Historically, the Baltimore Orioles have accumulated 71 head-to-head wins against the Red Sox, with 35 of those victories occurring on their home turf. However, recent trends show the Red Sox have won by multiple runs in 6 of their 8 victories against Baltimore this season. The Red Sox have also lost three of their last four games as favorites against the Orioles following a win, suggesting a potential for the Orioles to bounce back. The underdog has covered the run line in 16 of the recent matchups between these two teams.

Pick: Boston Red Sox Moneyline

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I'm backing the Boston Red Sox to secure another victory in this matchup. The pitching advantage with Brayan Bello over Dietrich Enns is substantial. Bello has demonstrated consistent performance this season and has a strong track record against the Orioles. Furthermore, Boston's bullpen is significantly more talented and rested, providing a strong late-game advantage. The Red Sox are in superior form overall, pushing for a playoff berth, while the Orioles are struggling and dealing with key injuries. While the Orioles have shown they can spring a surprise at home, the Red Sox's recent dominance in this head-to-head series, including winning by multiple runs in most of their victories against Baltimore this season, makes them the clear favorite. The sharp money also aligns with the Red Sox moneyline, showing a 56.64% sharp win percentage for Boston.

Top Player Prop Picks

Trevor Story Over 1.5 Total Bases (+135)

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Trevor Story has been a major catalyst for the Red Sox's success this season, rediscovering his power stroke with 21 home runs and 23 stolen bases. He boasts a strong .285 batting average and .508 slugging percentage against left-handed pitching, which is particularly relevant against Orioles' lefty starter Dietrich Enns. The Red Sox are 19-1 when Story homers this season, highlighting his significant impact on the team's offensive output. This prop is available at FOX Sports.

Brayan Bello Over 4.5 Strikeouts (-130)

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Brayan Bello enters this game with a solid 9.1 K/9 rate this season. In his last five starts against the Orioles, he has recorded 28 strikeouts, averaging 5.6 strikeouts per start, which is above this line. The Orioles' lineup features hitters like Jackson Holliday (116 strikeouts) and Gunnar Henderson (112 strikeouts) who have high strikeout totals this season, providing ample opportunities for Bello to hit the over on his strikeout prop. This prop is available at FOX Sports.

Gunnar Henderson Under 1.5 Total Bases (-150)

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While Gunnar Henderson has had some past success against Brayan Bello, the current conditions at Oriole Park at Camden Yards favor pitching. The park has transformed into a more pitcher-friendly venue, ranking 22nd in runs factor and home run factor. Bello's ground ball tendencies are well-suited for this environment, which could limit extra-base hits. Additionally, the Orioles' offense has struggled to generate consistent offense recently, which could further suppress Henderson's opportunities for total bases. This prop is available at FOX Sports.