Baltimore Orioles @ Washington Nationals Player Props, Picks and Predictions - 4/22/2025 6:45 PM EDT

We have your Baltimore Orioles @ Washington Nationals prop betting and game preview needs covered as the Washington Nationals hit the road to face the Baltimore Orioles.

Baltimore Orioles @ Washington Nationals Pick

Best Moneyline Odds: Orioles -135, Nationals +115 (Bet Now).
Best Total Odds: Over/Under 9 runs (Bet Now).

Game Info

Date: April 22, 2025
Time: 6:45 PM EDT
Location: Nationals Park, Washington, D.C.
TV: -

Baltimore Orioles @ Washington Nationals Preview

The Baltimore Orioles (9-12) and Washington Nationals (9-13) meet in what promises to be an intriguing matchup. The Orioles have struggled recently, going 2-4 as moneyline favorites, while the Nationals have been underdogs in most of their games, winning six of 16 contests in that role. Both teams are looking to gain momentum as they aim to climb their respective standings. With the total set at 9 runs, this game could see plenty of offensive action, especially given Baltimore's tendency to hit the over in four of their last five games.

Historic Head-to-Head Stats and Analysis

In their recent head-to-head matchups, the Orioles and Nationals have been evenly matched, with both teams trading wins. The Orioles have had a slight edge offensively, but the Nationals have shown resilience, particularly at home. These games have often been close, with several decided by one or two runs, making this matchup a compelling one for bettors.

Pick: Orioles Moneyline (-135)

The Orioles are the pick here on the moneyline. Despite their struggles as favorites, they have a stronger offensive lineup compared to the Nationals. Additionally, their recent games have shown an ability to score runs in bunches, which could be the difference-maker in this contest. The Nationals' inconsistency as underdogs further supports this pick.

Top Player Prop Picks

1. Over 1.5 Total Bases for Ryan Mountcastle

Ryan Mountcastle has been a key offensive contributor for the Orioles. With his ability to hit for power and consistency, he is a strong candidate to exceed 1.5 total bases in this game. Look for him to take advantage of a favorable pitching matchup.

2. Over 0.5 Home Runs for Joey Meneses

Joey Meneses has been a bright spot for the Nationals' offense. Facing a Baltimore pitching staff that has allowed its fair share of home runs, Meneses has a good chance to go deep in this game.

3. Over 4.5 Strikeouts for Orioles Starting Pitcher

The Orioles' starting pitcher has consistently hit this strikeout mark in recent outings. Against a Nationals lineup that has struggled with strikeouts, this prop offers solid value.

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