Baltimore Orioles @ Milwaukee Brewers Player Props, Picks and Predictions - 5/21/2025 1:10 PM EDT

We have your Baltimore Orioles @ Milwaukee Brewers prop betting and game preview needs covered as the Milwaukee Brewers host the Baltimore Orioles in what promises to be an exciting matchup.

Baltimore Orioles @ Milwaukee Brewers Pick

Best Moneyline Odds: Milwaukee Brewers -125, Baltimore Orioles +105.
Best Total Odds: Under 8.5 (-105), Over 8.5 (-115).

Game Info

Date: May 21, 2025
Time: 1:10 PM EDT
Location: American Family Field, Milwaukee, WI
TV: -

Baltimore Orioles @ Milwaukee Brewers Preview

The Milwaukee Brewers come into this game with momentum after a 5-2 victory over the Orioles in the previous matchup. The Brewers have been strong as moneyline favorites, winning 78.6% of games when favored at -125 or shorter odds. Meanwhile, the Orioles have struggled as underdogs, winning just 33.3% of their games in such situations. With the Brewers' solid pitching and timely hitting, they look to secure another win in this series.

Historic Head-to-Head Stats and Analysis

In their recent head-to-head matchups, the Brewers have had the upper hand. On May 19, 2025, the Brewers edged out the Orioles 5-4, and on May 20, 2025, they followed up with a convincing 5-2 victory. These results highlight Milwaukee's ability to capitalize on their opportunities against Baltimore, particularly at home.

Pick: Milwaukee Brewers Moneyline (-125)

widget-odds-mlb-su-10844-BAL-MIL

The Brewers have been dominant as favorites, and their recent performances against the Orioles further solidify their edge. With a strong home-field advantage and consistent play, Milwaukee is the safer pick to win outright.

Top Player Prop Picks

1. Total Runs Over 8.5 (-115)

widget-odds-mlb-ou-10844-BAL-MIL

Both teams have shown the ability to score runs in this series, with the Brewers putting up five runs in each of the last two games. The over is a solid play given the offensive potential on both sides.

2. Milwaukee Brewers -1.5 (+159)

widget-odds-mlb-ats-10844-BAL-MIL

The Brewers have won their last two games by multiple runs, showcasing their ability to control the game. Backing them to cover the spread offers great value.

3. Baltimore Orioles Total Runs Under 3.5 (-105)

The Orioles have struggled offensively in this series, scoring just six runs across two games. With Milwaukee's pitching staff in good form, the under on Baltimore's team total is a strong play.

New customer offers and more lines available at:

Free Picks available for new customers at: