Athletics @ Minnesota Twins Player Props, Picks and Predictions - 8/21/2025 1:10 PM EDT

We have your Athletics @ Minnesota Twins prop betting and game preview needs covered as the Athletics hit the road to face the Minnesota Twins.

Athletics @ Minnesota Twins Pick

Best Moneyline Odds: Athletics -116, Twins +100
Best Spread Odds: Athletics -1.0 (+106), Twins +1.5 (-155)
Best Total Odds: Over 9.5 (-104), Under 9.5 (-110)

Game Info

Date: August 21, 2025
Time: 1:10 PM EDT
Location: Target Field, Minneapolis, Minnesota
TV: -

Athletics @ Minnesota Twins Preview

The Athletics (58-70) are set to face the Minnesota Twins (58-68) in a Wednesday afternoon matchup at Target Field. The Athletics are coming off a 4-2 victory over the Twins yesterday, showcasing their recent strong form with a 7-3 record in their last 10 games. Right-hander Jack Perkins (2-2, 4.28 ERA) is expected to take the mound for the Athletics. Their offense has been powered by key hitters such as Jacob Wilson, who boasts a .312 batting average, Tyler Soderstrom with 23 home runs and 74 RBIs, Brent Rooker with 25 home runs and 72 RBIs, and Shea Langeliers, who has contributed 28 home runs and 60 RBIs this season.

The Minnesota Twins will look to bounce back from their recent loss to the Athletics. They have struggled to find consistency lately, holding a 3-7 record in their last 10 outings. Right-hander José Ureña will start for the Twins. The Twins' lineup features offensive threats like Byron Buxton, who has 25 home runs and 61 RBIs along with 18 stolen bases, and Trevor Larnach, who has chipped in 16 home runs and 50 RBIs.

Target Field, the venue for this game, is considered a slightly batter-friendly park, with a Park Factor of 102 and a home run factor of 103 for the 2023-2025 seasons, suggesting a potential for offense. Both teams are navigating through injuries, with the Athletics having several players on the IL, including Jacob Wilson and Max Muncy. The Twins are also missing key contributors like Pablo López and Christian Vázquez due to injuries.

Historic Head-to-Head Stats and Analysis

In their last 10 head-to-head matchups, the Minnesota Twins have a slight edge over the Athletics, holding a 6-4 record. The most recent encounter between these two teams took place on August 20, 2025, where the Athletics secured a 4-2 victory. An interesting trend to note is that the underdog has emerged victorious in each of the Twins' last four games played at Target Field.

Pick: Athletics Moneyline

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The Athletics present a compelling pick in this matchup, primarily due to their superior recent form. They have won 7 of their last 10 games, including yesterday's contest against the Twins, while Minnesota has struggled with a 3-7 record over the same span. The Athletics have also performed well against the spread on the road, holding a 38-27 ATS record away from home. While the Twins have a historical advantage in head-to-head matchups, the Athletics' current momentum and their performance as a road team make them a strong choice for the moneyline.

Top Player Prop Picks

Lawrence Butler Over 0.5 Hits

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Lawrence Butler has demonstrated a favorable historical matchup against Twins pitcher José Ureña. In their career encounters, Butler has a .600 batting average (3 hits in 5 plate appearances) and a .604 wOBA against Ureña. This strong past performance suggests he sees Ureña's pitches well, making him a solid candidate to record at least one hit in this game. The odds for this prop are Over 0.5 Hits (-245).

Nick Kurtz Over 1.5 Total Bases

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Nick Kurtz has been a significant power contributor for the Athletics throughout the season, leading the team with 25 home runs and 67 RBIs. His ability to hit for extra bases makes him a strong contender to exceed 1.5 total bases in this matchup. While there is no specific historical data against Twins pitcher José Ureña, Kurtz's season-long power numbers indicate a high potential for multiple bases. The odds for this prop are Over 1.5 Total Bases (-140).

Tyler Soderstrom Over 1.5 Total Bases

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Tyler Soderstrom is another key offensive force for the Athletics, having accumulated 23 home runs and 74 RBIs this season. His consistent power hitting makes him a strong candidate to surpass 1.5 total bases, especially considering Target Field's slightly batter-friendly environment. The odds for this prop are Over 1.5 Total Bases (+100).