A year ago this matchup would have not been half the matchup it is today. Not only are there playoff implications for both teams (seedings and clinching scenarios), but the Cards are looking solid. The Niners are rolling but are beatable, especially by a team that scalped the Seahawks on their own turf last week. This game could be a classic.

San Francisco @ Arizona (16.25pm ET)

**Matchup Difficulty: 68.2% **(the higher the score, the better the experts' success rate when picking these two teams. An 'average' matchup would be 62%)

Consensus: Arizona 56%

Top 5 Overall: Arizona 80%
Key Injuries:
San Francisco:
Mario Manningham, WR, Out
Arizona:
John Abraham, LB, Questionable
Best Pick Index:
_Table is sorted by overall success rate when picking these two teams on the road and at home. _

San Francisco

Arizona

Rank

Expert

Affiliation

Road %

Home %

Overall

Pick

1

Rich Eisen

NFL

100.00%

100.00%

100.0%

ARI

2

Don Banks

Sports Illustrated

100.00%

100.00%

100.0%

ARI

3

Tyson Langland

Bleacher Report

100.00%

85.71%

92.9%

ARI

4

K.C. Joyner

ESPN

85.71%

100.00%

92.9%

SFO

5

Ron Jaworski

ESPN

85.71%

100.00%

92.9%

ARI

6

John Halpin

FOX

100.00%

85.71%

92.9%

ARI

7

Kevin Patra

NFL

85.71%

100.00%

92.9%

ARI

8

Matt Smith

NFL

100.00%

85.71%

92.9%

SFO

9

Jamey Eisenberg

CBS

100.00%

71.43%

85.7%

SFO

10

Cris Carter

ESPN

100.00%

71.43%

85.7%

ARI

11

Ryan Fowler

FOX

100.00%

71.43%

85.7%

SFO

12

Chris Brockman

NFL

100.00%

71.43%

85.7%

ARI

13

Steve Mariucci

NFL

100.00%

71.43%

85.7%

SFO

14

Michael David Smith

PFT

100.00%

71.43%

85.7%

ARI

15

Pickwatch

Pickwatch

100.00%

71.43%

85.7%

ARI

16

Sam Monson

ProFootballFocus

100.00%

71.43%

85.7%

ARI

17

Vinnie Iyer

Sporting News

100.00%

71.43%

85.7%

ARI

18

Erik Frenz

Bleacher Report

85.71%

85.71%

85.7%

SFO

19

Prediction Machine

CBS

85.71%

85.71%

85.7%

SFO

20

Will Brinson

CBS

85.71%

85.71%

85.7%

SFO

21

Rick Drummond

ProFootballFocus

85.71%

85.71%

85.7%

ARI

22

Nate Davis

USA Today

85.71%

85.71%

85.7%

ARI

23

Steve Wyche

NFL

85.71%

83.33%

84.5%

ARI

24

Adam Rank

NFL

83.33%

83.33%

83.3%

SFO

25

Andrea Hangst

Bleacher Report

85.71%

71.43%

78.6%

ARI

26

Brad Gagnon

Bleacher Report

85.71%

71.43%

78.6%

SFO

27

Matt Bowen

Bleacher Report

100.00%

57.14%

78.6%

SFO

28

Ty Schalter

Bleacher Report

85.71%

71.43%

78.6%

ARI

29

Dave Richard

CBS

85.71%

71.43%

78.6%

SFO

30

Pete Prisco

CBS

71.43%

85.71%

78.6%

ARI

31

Ryan Wilson

CBS

85.71%

71.43%

78.6%

ARI

32

Keyshawn Johnson

ESPN

85.71%

71.43%

78.6%

SFO

33

Seth Wickersham

ESPN

85.71%

71.43%

78.6%

SFO

34

Whatifsports

FOX

100.00%

57.14%

78.6%

SFO

35

Chris Law

NFL

85.71%

71.43%

78.6%

ARI

36

Chris Wesseling

NFL

100.00%

57.14%

78.6%

ARI

37

Gregg Rosenthal

NFL

100.00%

57.14%

78.6%

ARI

38

Heath Evans

NFL

71.43%

85.71%

78.6%

ARI

39

Marc Sessler

NFL

85.71%

71.43%

78.6%

SFO

40

Gordon McGuinness

ProFootballFocus

100.00%

57.14%

78.6%

ARI

41

Steve Palazzolo

ProFootballFocus

85.71%

71.43%

78.6%

ARI

42

Lindsay H. Jones

USA Today

85.71%

71.43%

78.6%

ARI

43

Brian Baldinger

NFL

83.33%

71.43%

77.4%

No Pick

44

Marshall Faulk

NFL

71.43%

83.33%

77.4%

SFO

45

Chris Hansen

Bleacher Report

100.00%

42.86%

71.4%

ARI

46

Zach Kruse

Bleacher Report

100.00%

42.86%

71.4%

ARI

47

John Breech

CBS

100.00%

42.86%

71.4%

ARI

48

Josh Katzowitz

CBS

71.43%

71.43%

71.4%

ARI

49

Eric Allen

ESPN

71.43%

71.43%

71.4%

SFO

50

Mike Ditka

ESPN

100.00%

42.86%

71.4%

SFO

51

Michael Fabiano

NFL

100.00%

42.86%

71.4%

ARI

52

Michael Silver

NFL

71.43%

71.43%

71.4%

ARI

53

Black Tie

NFL

100.00%

42.86%

71.4%

ARI

54

Jarrett Bell

USA Today

71.43%

71.43%

71.4%

ARI

55

Simon Samano

USA Today

71.43%

71.43%

71.4%

SFO

56

Mike Freeman

Bleacher Report

85.71%

57.14%

71.4%

ARI

57

Mark Schlereth

ESPN

85.71%

57.14%

71.4%

SFO

58

Merill Hoge

ESPN

85.71%

57.14%

71.4%

ARI

59

Joel Beall

FOX

85.71%

57.14%

71.4%

SFO

60

Henry Hodgson

NFL

85.71%

57.14%

71.4%

SFO

61

Michael Irvin

NFL

85.71%

57.14%

71.4%

SFO

62

NFL FAN PICKS

NFL

85.71%

57.14%

71.4%

SFO

63

Accuscore

Accuscore

85.71%

57.14%

71.4%

SFO

64

Les Carpenter

Yahoo

100.00%

33.33%

66.7%

No Pick

65

Matt Miller

Bleacher Report

71.43%

57.14%

64.3%

SFO

66

Michael Schottey

Bleacher Report

85.71%

42.86%

64.3%

SFO

67

Jason La Canfora

CBS

71.43%

57.14%

64.3%

ARI

68

Adam Schefter

ESPN

85.71%

42.86%

64.3%

ARI

69

Chris Mortensen

ESPN

57.14%

71.43%

64.3%

ARI

70

Mike Golic

ESPN

85.71%

42.86%

64.3%

SFO

71

Pick ‘em

ESPN

85.71%

42.86%

64.3%

SFO

72

Dan Hanzus

NFL

85.71%

42.86%

64.3%

ARI

73

Dave Damashek

NFL

71.43%

57.14%

64.3%

ARI

74

Elliot Harrison

NFL

85.71%

42.86%

64.3%

SFO

75

Kurt Warner

NFL

100.00%

28.57%

64.3%

SFO

76

Mike Florio

PFT

71.43%

57.14%

64.3%

ARI

77

Khaled Elsayed

ProFootballFocus

71.43%

57.14%

64.3%

SFO

78

Nathan Jahnke

ProFootballFocus

85.71%

42.86%

64.3%

ARI

79

Frank Schwab

Yahoo

85.71%

42.86%

64.3%

SFO

80

Yahoo Users

Yahoo

85.71%

42.86%

64.3%

SFO

81

Jim Corbett

USA Today

100.00%

28.57%

64.3%

SFO

82

Pete O'Brien

USA Today

71.43%

57.14%

64.3%

ARI

83

Tom Pelissero

USA Today

85.71%

42.86%

64.3%

ARI

84

Knox Bardeen

Bleacher Report

85.71%

28.57%

57.1%

SFO

85

Tom Jackson

ESPN

85.71%

28.57%

57.1%

SFO

86

Adam Meyer

FOX

85.71%

28.57%

57.1%

SFO

87

Melissa Stark

NFL

71.43%

42.86%

57.1%

ARI

88

Shaun O'Hara

NFL

85.71%

28.57%

57.1%

ARI

89

Sterling Sharpe

NFL

57.14%

57.14%

57.1%

ARI

90

Coin Toss

None

42.86%

71.43%

57.1%

SFO

91

Neil Hornsby

ProFootballFocus

57.14%

57.14%

57.1%

SFO

92

Warren Sapp

NFL

71.43%

28.57%

50.0%

SFO

93

Ben Stockwell

ProFootballFocus

71.43%

28.57%

50.0%

SFO

For more updates from Pickwatch, follow us on twitter or Facebook. Check back for more previews of week 17's matchups, helping you to decide who to trust in this week's biggest games. Missing picks will be updated... well, they'll be updated when the picks are actually made!

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