We like to mix things up, so here we take a look at which of week 10's heavy underdogs have the best chance of flying in the face of experts. And facts. We rank 5 'dogs by how likely they are to cause an upset, and give you as many reasons as we can think of to give some hope to fans of those teams.

All of the teams below are picked by less than 10% of experts in our weekly straight up standings. Unfortunately, while we love an underdog, we can't work miracles and they're still long-shots.

St. Louis (@ Cardinals, 4.25pm)

Reasons they can cause an upset:

  1. Let's start with the obvious: They caused a major upset last week against the 49ers on the road, in a game not a single expert picked them to win. They also beat the Seahawks in week 7 when 100% of experts picked Seattle, and Tampa Bay in week 2 when experts favored the Bucs 97%. That's good upset pedigree right there.
  1. The defensive line is the best in football. Period. They sacked a mobile, elusive QB in Colin Kaepernick 8 times last week - what can they do to an ageing Carson Palmer coming off a recent injury?
  1. Although Austin Davis had an abysmal 105 yards passing last week, the Rams are not slaves to his performances. They beat the Seahawks when he threw for 155yds by utilizing trick plays such as the punt return by Stedman Bailey and a last-gasp fake-punt to ice the game (sort of). In short, Jeff Fisher has balls and a brain. Unlike me, he can engage both at the same time.

Carolina (@ Philadelphia, Monday 8pm)

Reasons they can cause an upset:

  1. SANCHIZE BABY! Does anybody really know enough about Mark Sanchez to say he won't have an absolute New York Jet of a performance and simply hand Carolina a victory via a 4 INT game with 17 fumbles?
  1. For all the Panthers are in a slump, they're really at heart the same team that beat the Bears and Lions, while they also tied the Bengals in week 6 (which by the way, caused havoc with some media outlets definition of 'wins' and 'losses'). Sure, Cam Newton has the completion percentage of a man wearing a blindfold over the last few weeks, but always remember that the Panthers have wins in them.
  1. DeAngelo WIlliams is back. A lot of people have questioned the Panthers' decision to pay Williams big money a few years back, but although his stats are down, his role in the team is crucial. Who do you trust to run the ball when you need to? Jonathan Stewart? Fozzy Whitaker? Those sound like terrible ideas when you've got Williams. His stabilizing presence will be good for Newton and good for the Panthers

Jacksonville (vs Cowboys, London, 1pm)

Reasons they can cause an upset:

  1. Tony Romo will start, but will he finish? I'd hate to incite violence in any way, but if Romo was to be injured early on by the underrated Jags D-line? Well, then it would be Brandon Weeden time. And we all know that gives any team a chance.
  1. The Jags have played in London twice before as the home team, and know what to expect from the Wembley turf. It's actually the same 'Grassmaster' turf used in places like Denver and Philly, but Britain being Britain (I'm allowed to say this) the weather makes it a volatile surface to play on.
  1. Erm... really struggling here. Owner Shahid Khan has the greatest mustache in recent NFL history.

San Francisco (@ New Orleans, 1pm)

Reasons they can cause an upset:

  1. Although they were sucker-punched by the Rams last week, the 49ers actually put up a respectable amount of yards. If they can be more efficient, the New Orleans defence is ripe for picking apart.
  1. The 49ers defence is good enough to keep them in the game. Of course, Drew Brees is also the second best QB they faced all year, and the first was Peyton Manning (who put up 42pts) but whatever. We're trying to be positive here. Don't be a negative nelly.
  1. The 49ers are 3-1 when they have 100+ rushing yards in a game this season. Jim Harbaugh's indifference to the run game is a mystery, but if he figures it out (presumably by shouting at himself in a room somewhere, because that sounds like a Harbaugh-esque thing to do) in his own mind, the 49ers can certainly give themselves a shot. Oh, and would you argue with this face?

frankgore

Chicago (@ Green Bay, 8:30pm)

Reasons they can cause an upset:

  1. Tricky one this. Well, the Packers, for all the hype, are coming off a poor let-down performance against the Saints, who rode a strong running game to victory. The Bears have a strong running game, ergo this situation is definitely exactly the same. Ahem.
  1. Jay Cutler just has that annoying (or not if you're a Bears fan) of having a really good game when people doubt him most. Basically, his entire life is a big troll. FIrst it was Leinart, then Plummer, then Shanahan, then Jerry Angelo, fans of Kristen Cavalleri, and now it's his critics. As soon as everyone thinks they've got him figured out, that's when Jay's at his most dangerous.
  1. Despite being as porous as the string vest worn by Bennett in 1985 Rocket-Launcher-fest Commando, the Bears defence is actually not as bad as the Packers, particularly against the rush, a category in which Green Bay rank dead last in the NFL. If the Bears can hold up against Aaron Rodgers and his receiving weapons - and that's a huge if - they can likely control the game with Matt Forte.

That's our opinion - what about you? Let us know here or in the forum if you think a team can pull an upset this weekend. You can follow us on twitter for more news and live updates on which experts have picked each week.